N/A
Completed N=100
Effect of Nurse-led Education on Parent's Anxiety and Depression on Managing Side Effects of Chemotherapy
Chemotherapy Effect
Source: ClinicalTrials.gov NCT03753542 ↗
Enrolled (actual)
100
Serious AEs
—
Results posted
Jul 2022
Primary outcomePrimary: Depression, Anxiety and Stress Scale - 21 (DASS-21) — 6.44; 9.72; 2.63; 6.11 score on a scale
Summary
ABSTRACT
Background:
Today, a wide range of pediatric cancers is treated by chemotherapy. More than 21 side effects of chemotherapy have been identified. Among those nausea; vomiting, infection and anemia are most common. The adverse effects are normally managed by the parents at home. Ineffective coping and lack of knowledge about chemotherapy side effect management leads parents stress. Contemporary research evidence that Nurse-led education, booklet providence and follow up about chemotherapy and side effect management, help to decrease parents anxiety and depression.
Objectives:
To measure the effect of nurse-led multimedia education, booklet providence and telephonic follow up about chemotherapy and side effects management on parents anxiety and depression of children receiving chemotherapy for the first time.
Methodology:
A randomized control trial will be conducted in the department of chemotherapy at Indus Children Cancer Hospital Karachi from March 2018 to August 2018 on parents of children below 18 years of age undergoing chemotherapy for the first time. Total 100 parents will be randomly divided into Intervention group (n=50) and Control Group (n=50). The Intervention group will received multimedia education, booklet and weekly tele-nursing follow-up about chemotherapy and side effects management. The Control group will receive routine care. Parent's anxiety and depression will be identified by using DASS-21 and generalized estimating estimation will be used to analyzed the data.
Keywords:
Nurse-led, Multimedia education, Booklet, telephonic follow-up, chemotherapy, side effects, parents, anxiety, depression, children, cancer
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Depression, Anxiety and Stress Scale - 21 (DASS-21) |
6.44; 9.72; 2.63; 6.11; 4.2; 6.61 | — |
Eligibility Criteria
Inclusion Criteria
- Parents along with their Children younger than 18 years of age Note: (Here Child age was taken as Inclusion criteria for Parents, because child age is evident for impact on Parents Psychology, in local study no association of Parents age was evident)
- Parents along with their children newly diagnosed with cancer in last three weeks
- Parents along with their children schedule to receive first time chemotherapy in the outpatient department
Exclusion Criteria
- Parents along with their children refused to participate
- Parents along with their children already receiving interventions like multimedia education, booklet providence and telephonic follow up for chemotherapy and side effect management
- Parents taking medicine for their anxiety and depression. (e.g. Anxiolytics/ Antidepressant)
- Parents showing uneasiness and discomfort during educational session.
Data sourced from ClinicalTrials.gov (NCT03753542). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.