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N/A N=44 Basic Science

Variability and Specificity in Reactive Stabilization Movements to Diverse Slip Perturbations

Slip Perturbations

Enrolled (actual)
44
Serious AEs
0.0%
Results posted
May 2025
Primary outcome: Primary: Fall Rates — 18.3; 16.0 Percentage of trials resulting in falls.

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Administered Slip Perturbations (Other)
Age
Adult, Older Adult · 19+ yrs
Sex
All
Sponsor
University of Nebraska
Primary completion
Jan 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Fall Rates
18.3; 16.0
SECONDARY
Total Heel Displacement of the Slipping Foot Following Slip Perturbation
SECONDARY
Trunk Angular Momentum Following Slip Perturbation
SECONDARY
Position of the Recovery Step Following Slip Perturbation
SECONDARY
Coefficient of Variation of Stride Time Time Series
SECONDARY
Maximum Heel Sliding Velocity of the Slipping Foot Following Slip Perturbation
SECONDARY
Time of the Recovery Step Following Slip Perturbation
SECONDARY
Sample Entropy of Stride Time Time Series

Summary

Recent research on slips has shown that use of perturbation training to improve specific motor skills to resist slips can vastly reduce falls. However, these interventions have only addressed slips occurring at heel-strike, and not the diverse range of slipping disturbances presented by a complex environment. This project will focus on slips that occur across the gait cycle, and the reactive stabilization movements that follow. Participants from two age groups will be enrolled: younger (19 - 35 years of age) and older (65-79 years of age). Each participant will participate in 3 visits within the span of 1 week. On the initial visit, participants will perform informed consent, have demographic and body measurement information collected and complete medical and physical activity questionnaires. Upper and lower body strength will be measured using a hand-held dynamometer during the first and last visits. On each of the three visits, subjects will perform a gait variability assessment followed by a diverse slip perturbation assessment. Participants will complete four slips in each of early, middle, and late stance on each visit. Measures of falls, slip severity, and reactive stabilization movements will be calculated.

Eligibility Criteria

Inclusion Criteria

  • Age 19-35 years for younger adults group, or age 65-79 years for older adults group.

Exclusion Criteria

  • Uncontrolled hypertension
  • Peripheral arterial disease
  • Vertigo
  • Meniere's disease
  • Chronic dizziness
  • History of back or lower extremity injury
  • Surgery that affects the subject's mobility
  • Any neurological disease or impairment that affects limits the ability to walk, e.g. Stroke, Parkinson's disease, Multiple sclerosis
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03755336). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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