Phase 1 N=36 Randomized Double-blind Basic Science

Effect of Stimulant Drugs on Social Perception

Healthy · MDMA ('Ecstasy')

Bottom Line

View on ClinicalTrials.gov: NCT03790618 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jan 2024

Primary outcome: Primary: Responses to Affective Touch — -1.24; 0.12; 0.19; 0.25 units on a scale

Study Design & Population

Study type: Interventional
Phase: Phase 1
Interventions: 3,4-Methylenedioxymethamphetamine (Drug); methamphetamine (Drug)
Age: Adult · 18+ yrs
Sex: All
Sponsor: University of Chicago
Primary completion: Aug 2018

Outcome Measures

Outcome	Result	p-value
PRIMARY Responses to Affective Touch	-1.24; 0.12; 0.19; 0.25	—

Summary

The study will improve our understanding of the "prosocial" effects of ± 3,4-Methylenedioxymethamphetamine (MDMA), relative to a prototypical stimulant, methamphetamine (MA). The investigators seek to characterize the "uniquely social" effects of MDMA.

Eligibility Criteria

Inclusion Criteria

High school degree
English fluency
Healthy
Has used MDMA

Exclusion Criteria

Pregnant or trying to become pregnant
Any medical or psychiatry condition

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03790618). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.