N/A
N=97
Hepatic Vein Flow During Orthotopic Liver Transplantation as Predictive Factor for Postoperative Graft Function
Postoperative Graft Function
Bottom Line
View on ClinicalTrials.gov: NCT03814031 ↗Enrolled (actual)
97
Serious AEs
0.0%
Results posted
Sep 2024
Primary outcome: Primary: EAD — 1.23; 2.19; 0.87; 1.54 L/kg/min
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- NO internvention (Other)
- Age
- Pediatric, Adult, Older Adult
- Sex
- All
- Sponsor
- Henry Ford Health System
- Primary completion
- Dec 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY EAD |
1.23; 2.19; 0.87; 1.54 | — |
| SECONDARY Acute Rejection |
0.738; 1.535; 0.571; 1.101 | — |
| SECONDARY Prolonged (>Seven Days) Time to Normalize Total Bilirubin (TIME T-bil) |
1.086; 2.051; 0.806; 1.351 | — |
| SECONDARY Prolonged (>Seven Days) Time to Normalize INR (TIME Inr) |
1.081; 1.484; 0.954; 1.050 | — |
| SECONDARY Prolonged (>Seven Days) Time to Normalize Platelet Count (TIME Plt). |
1.341; 1.379; 0.829; 1.024 | — |
Summary
Hepatic vein flow (HVF) assessment using transesophageal echocardiography (TEE) has a potential to predict postoperative graft function in orthotopic liver transplant (OLT). Investigators will measure HVF using TEE and assess the correlation with postoperative graft function indices such as early allograft dysfunction(EAD), prolonged INR, platelet, and total bilirubin.
Eligibility Criteria
Inclusion Criteria
Orthotopic liver transplants which uses TEE intraoperatively Must be Piggy back technique
-
Exclusion Criteria
TEE absolute contraindication patient refusal
Data sourced from ClinicalTrials.gov (NCT03814031). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.