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N/A Completed N=97

Hepatic Vein Flow During Orthotopic Liver Transplantation as Predictive Factor for Postoperative Graft Function

Postoperative Graft Function
Source: ClinicalTrials.gov NCT03814031 ↗
Enrolled (actual)
97
Serious AEs
0.0%
Results posted
Sep 2024
Primary outcomePrimary: EAD — 1.23; 2.19; 0.87; 1.54 L/kg/min

Summary

Hepatic vein flow (HVF) assessment using transesophageal echocardiography (TEE) has a potential to predict postoperative graft function in orthotopic liver transplant (OLT). Investigators will measure HVF using TEE and assess the correlation with postoperative graft function indices such as early allograft dysfunction(EAD), prolonged INR, platelet, and total bilirubin.

Outcome Measures

OutcomeResultp-value
PRIMARY
EAD
1.23; 2.19; 0.87; 1.54
SECONDARY
Acute Rejection
0.738; 1.535; 0.571; 1.101
SECONDARY
Prolonged (>Seven Days) Time to Normalize Total Bilirubin (TIME T-bil)
1.086; 2.051; 0.806; 1.351
SECONDARY
Prolonged (>Seven Days) Time to Normalize INR (TIME Inr)
1.081; 1.484; 0.954; 1.050
SECONDARY
Prolonged (>Seven Days) Time to Normalize Platelet Count (TIME Plt).
1.341; 1.379; 0.829; 1.024

Eligibility Criteria

Inclusion Criteria

Orthotopic liver transplants which uses TEE intraoperatively Must be Piggy back technique

-

Exclusion Criteria

TEE absolute contraindication patient refusal

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03814031). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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