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N/A N=1,238,835 Randomized Treatment

Improving BP Control in Diverse Populations Using BP MAP

Hypertension

Enrolled (actual)
1,238,835
Serious AEs
Results posted
Mar 2025
Primary outcome: Primary: Change in Blood Pressure Control, % of Patients — 2.8; 1.6; -0.4 percentage of patients

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Self-Guided M.A.P. BP Improvement Program (Other); Full Support M.A.P. BP Improvement Program (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of California, San Francisco
Primary completion
Feb 2021

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Blood Pressure Control, % of Patients
2.8; 1.6; -0.4
SECONDARY
Change in Improvement in Blood Pressure, % of Patients
-3.4; -5.4; -3.1
SECONDARY
Change in Confirmatory Repeated Blood Pressure Measurement, % of Visits
19.8; 11.6; 0.1
SECONDARY
Change in Medication Intensification, % of Visits
-1.6; -3.4; -0.1
SECONDARY
Change in Average Systolic Blood Pressure (SBP) Reduction After a Medication Intensification Visit, mmHg
2.3; -1.6; -1.1
SECONDARY
Change in Repeat Visit in 4 Weeks After a Visit With Elevated BP, % of Visits
-0.8; -2.0; -0.6
SECONDARY
Change in Use of Fixed Dose Combination Product Among Patients Taking 2 or More Classes of Medications, % of Patients
1.6; -0.1; -0.7
SECONDARY
Change in Use of a CCB or Thiazide or Thiazide-like Diuretic Among African-American Patients on at Least One Medication, % of Patients
-0.9; -0.1; 0.0
SECONDARY
Change in Terminal Digit = Zero, % of Measurements
0.8; 0.9; -0.6
SECONDARY
Change in Blood Pressure Controlled to 2017 Guideline Goal, % of Patients
-1.5; -1.1; -0.5

Summary

BP-MAP is a cluster randomized controlled trial (RCT) designed to compare the effectiveness of BP lowering from a clinic-based quality improvement program with Full Support (dedicated practice facilitation) vs. a Self-Guided version of the program. The American Medical Association (AMA) developed the framework for the interventions.

Eligibility Criteria

ACTIVE CLINICS

For inclusion as an Active Clinic in this study, clinics may participate must be able to identify:

  • A Site Champion who works at the clinic and who is willing to take primary responsibility for implementing the M.A.P. intervention
  • A Physician Champion who works at the clinic and who is willing to advocate actively for the M.A.P. intervention
  • A Practice Change Facilitator willing to attend a 1-day training and help guide implementation of the M.A.P intervention for Full Support sites, with the support of AMA staff (may be the Site Champion or Physician Champion, or a person with regional responsibilities who can support multiple sites)

Sites will be excluded if they:

  • Have implemented any high blood pressure quality improvement component from the M.A.P. BP improvement program as part of Target: BP or from the AMA or Target: BP websites
  • Are currently involved in an ongoing clinical trial or grant funded project related to high blood pressure or hypertension

USUAL CARE CLINICS:

Usual Care Clinics will include PCORnet Datamarts participating in BP TRACK, a concurrently-running BP Control Registry within PCORnet that will provide quarterly datamart-level estimates of BP control and other aggregate metrics relevant to BP control. All participating datamarts will be included, with the following exceptions:

  • Datamarts with any Active Clinics participating in BP MAP will be excluded
  • Datamarts that obscure dates via date-shifting will be excluded, as this will not allow for control of concurrent secular trends

PATIENTS

Within clinics (Active or Usual Care), patients will be eligible (and identified from the electronic health record) if they meet National Quality Forum BP Control Metric (NQF 0018) criteria:

  • Age 18-85 on the date of analysis
  • At least one outpatient encounter with a diagnosis of hypertension during the first six months of the measurement year (ending on the date of analysis)
  • No diagnosis or evidence of end-stage renal disease on or prior to the end of the measurement year
  • No pregnancy during the measurement year
  • No admission to an inpatient setting during the measurement year
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03818659). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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