N/A
N=176
Adenoma Miss Rate With Water Exchange vs Carbon Dioxide Colonoscopy
Colonic Adenoma · Water Exchange Colonoscopy
Bottom Line
View on ClinicalTrials.gov: NCT03832322 ↗Enrolled (actual)
176
Serious AEs
0.0%
Results posted
May 2019
Primary outcome: Primary: Percentage of Overall Detected Adenomas Missed During the First Right-Colon Colonoscopy — 33.8; 17.5 percentage of detected adenomas
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Water exchange colonoscopy (Procedure); CO2 insufflation colonoscopy (Procedure)
- Age
- Adult, Older Adult · 20+ yrs
- Sex
- All
- Sponsor
- Evergreen General Hospital, Taiwan
- Primary completion
- Nov 2018
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percentage of Overall Detected Adenomas Missed During the First Right-Colon Colonoscopy |
33.8; 17.5 | — |
| PRIMARY Percentage of Overall Detected Adenomas Missed During the First Proximal-Colon Colonoscopy |
15.5; 30.4 | — |
Summary
This was an observational study comparing consecutive group of WE and CO2 insufflation in terms of right and proximal colon AMR by tandem colonoscopy.
Eligibility Criteria
Inclusion Criteria
- Consecutive patients aged 20 years or older undergoing colonoscopy for screening and surveillance indications were considered for enrollment.
Exclusion Criteria
- familial adenomatous polyposis and hereditary non-polyposis CRC syndrome, personal history of inflammatory bowel disease, previous colonic resection, inability to achieve cecal intubation, obstructive lesions of the colon, poor colon preparation, inability to completely remove a polyp, gastrointestinal bleeding, allergy to fentanyl or midazolam, American Society of Anesthesiology classification of physical status grade 3 or higher, mental retardation, pregnancy, and refusal to provide a written informed consent.
Data sourced from ClinicalTrials.gov (NCT03832322). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.