N/A
N=262
Right Colon Polyp Miss Rates of Water Exchange and Carbon Dioxide Insufflation Colonoscopy
Right Colon Adenoma Miss Rate · Right Colon Hyperplastic Polyp Miss Rate
Bottom Line
View on ClinicalTrials.gov: NCT03845933 ↗Enrolled (actual)
262
Serious AEs
0.0%
Results posted
Dec 2019
Primary outcome: Primary: Percentage of Adenomas and Hyperplastic Polyps Missed During Initial Right Colon Examination — 18.0; 36.7 percentage of all missed polyps
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Colon polypectomy (Procedure)
- Age
- Adult, Older Adult · 45+ yrs
- Sex
- All
- Sponsor
- Evergreen General Hospital, Taiwan
- Primary completion
- Oct 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percentage of Adenomas and Hyperplastic Polyps Missed During Initial Right Colon Examination |
18.0; 36.7 | — |
Summary
This will be a prospective randomized controlled trial comparing CO2 insufflation and WE in terms of right colon combined adenoma miss rate (AMR) and hyperplastic polyp miss rate (HPMR) by tandem inspection. It will be a single-site study conducted in Taiwan.
Eligibility Criteria
Inclusion Criteria
- Consecutive patients aged 45 years or older undergoing colonoscopy for screening, surveillance, and positive FIT will be considered for enrollment.
Exclusion Criteria
- familial adenomatous polyposis and hereditary non-polyposis CRC syndrome, personal history of CRC or inflammatory bowel disease, previous colonic resection, obstructive lesions of the colon, gastrointestinal bleeding, allergy to fentanyl, midazolam or propofol, American Society of Anesthesiology (ASA) classification of physical status grade 3 or higher, mental retardation, pregnancy, and refusal to provide a written informed consent.
Data sourced from ClinicalTrials.gov (NCT03845933). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.