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N/A N=272 Randomized Treatment

Evaluation of the CleanSweep™ Closed Suction System on Length of Mechanical Ventilation and Ventilator-Associated Events

Mechanical Ventilation Complication

Enrolled (actual)
272
Serious AEs
0.0%
Results posted
Mar 2023
Primary outcome: Primary: Length of Time on a Mechanical Ventilator — 70.6; 72.2 hours

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
CleanSweep Closed Suction System (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Rush University Medical Center
Primary completion
May 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Length of Time on a Mechanical Ventilator
70.6; 72.2
SECONDARY
Time to First Successful Spontaneous Breathing Trial (SBT)
45.7; 46.7
SECONDARY
Length of Time in the Intensive Care Unit
7.8; 9
SECONDARY
Length of Total Hospital Stay
13.9; 14.7
SECONDARY
Number of Participants With Ventilator-associated Events
16; 9

Summary

The primary aim of this study is to evaluate the CleanSweep™ Closed Suction System on time to first successful spontaneous breathing trial in mechanically ventilated patients in the medical intensive care unit. Secondary aims of this study are to evaluate the use endotracheal tube sweeping compared to closed suctioning effect on length of mechanical ventilation, length of ICU stay, length of total hospital stay, and occurrence of ventilator-associated events.

Eligibility Criteria

Inclusion Criteria

  • Orally intubated patient with endotracheal tube
  • Mechanically ventilated less than 24 hours prior to enrollment

Exclusion Criteria

  • Less than 18 years old
  • Tracheostomy tube
  • Extracorporeal membrane oxygenation
  • Transfer from outside hospital with more than 24 hours of mechanical ventilation
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03868735). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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