N/A
Completed N=201
Opiates Prescribing for Knee Arthroscopies and ACL Reconstruction
Knee Injuries · ACL Injury
Source: ClinicalTrials.gov NCT03876743 ↗
Enrolled (actual)
201
Serious AEs
0.0%
Results posted
Sep 2020
Primary outcomePrimary: Numeric Pain Rating Scale (NPRS) Pain Score — 5.2; 5.3; 5.0; 5.6 score on a scale
Summary
The purpose of the study is to determine if opiates are required to achieve adequate analgesia after knee arthroscopy and ACL reconstruction in outpatient surgery.
The investigators hypothesize that patients are frequently prescribed more opiates than are needed after surgery, resulting in excess medications that are at risk for misuse, diversion and contribution to the opioid epidemic.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Numeric Pain Rating Scale (NPRS) Pain Score |
5.2; 5.3; 5.0; 5.6 | — |
| PRIMARY Opiate Count |
3.5; 4.5; 9.5; 12.2 | — |
| PRIMARY Side Effects, 24 Hours Post-op |
7; 5; 23; 24 | — |
| PRIMARY Numeric Pain Rating Scale (NPRS) Pain Scores |
2.0; 2.4; 2.9; 2.6 | — |
| PRIMARY Side Effects |
7; 5; 24; 25 | — |
| PRIMARY Number of Participants With Side Effects |
7; 5; 24; 25 | — |
| PRIMARY Refill Requests |
1; 0; 5; 7 | — |
| PRIMARY Still Taking Opiates? |
3; 0; 5; 5; 45; 47 | — |
Eligibility Criteria
Inclusion Criteria
- All patients presenting to Northwestern Memorial Hospital (NMH) or to a Northwestern orthopaedic surgery faculty member's clinic undergoing knee arthroscopy with meniscus repair and/or debridement
- 18 years old or greater
- Ability to read and speak English
Exclusion Criteria
- Revision surgery
- Oncologic surgery
- Arthroscopic knee surgery that involves procedures other than ACL or the meniscus (i.e PCL, LCL, MPFL)
- Patients currently taking narcotics, chronic pain management patients, history of substance abuse
- Adults unable to consent
- Individuals who are not yet adults (infants, children, teenagers)
- Pregnant women
- Prisoners
- Patients currently taking narcotics, chronic pain management patients, history of substance abuse
Data sourced from ClinicalTrials.gov (NCT03876743). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.