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N/A N=72 Randomized Prevention

To Measure Pain Perception Following De-Epithelized Free Gingival Graft Harvesting

Gingival Recession · Palate; Wound

Enrolled (actual)
72
Serious AEs
0.0%
Results posted
Aug 2024
Primary outcome: Primary: Pain Assessment (0=No Pain to 10=Worst) — 4.2; 1.9; 2.2; 1 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
palatal wound will be cover with collagen and sutures (Diagnostic_test); palatal wound covered with platelet rich fibrin (Diagnostic_test); palatal wound covered with a collagen sponge and cyanoacrylate (Diagnostic_test); palatal wound covered with a stent (Diagnostic_test)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of Alabama at Birmingham
Primary completion
Jul 2021

Outcome Measures

OutcomeResultp-value
PRIMARY
Pain Assessment (0=No Pain to 10=Worst)
4.2; 1.9; 2.2; 1
PRIMARY
Bleeding Assessment
1; 0.6; 0.9; 0.7
SECONDARY
Activity Tolerance
2.4; 1.5; 1.8; 1.3
SECONDARY
Amount of Swelling
2.2; 1.3; 1.4; 1.3
SECONDARY
The Need for Painkiller
2.1; 2; 2.2; 1.5

Summary

This randomized clinical comparative study will evaluate the postoperative pain following the FGG graft harvest procedure technique covered by four different methods for coverage of the palatal donor site.

Eligibility Criteria

Inclusion Criteria

  • English speaking
  • At least 18 years old- 70 years old
  • Must be a patient of the UAB Dental School
  • Able to read and understand informed consent document
  • Patients needing soft tissue graft with teeth that have miller class I or II recession (>=2mm) on the facial aspects
  • Presence of periodontally healthy teeth at the recipient site.
  • Ability of the participants to maintain good oral hygiene
  • Patient not pregnant or breastfeeding
  • Not taking medications known to cause gingival enlargement

Exclusion Criteria

  • Non-English speaking
  • Less than 18 years old, older than 70 years old
  • Smokers/tobacco users
  • Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing
  • Patients that have severe gingival recession (Miller class III and IV) or < 2 mm.
  • Presence of periodontal disease at the recipient site.
  • Poor oral hygiene
  • Patient pregnant or breastfeeding
  • Taking medications known to cause gingival enlargement
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03895476). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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