N/A
Completed N=54
Effects of Breaking up Prolonged Sitting on Postprandial Cardiometabolic Disease Risk Markers in South Asian Adults
Cardiovascular Risk Factor · Cardiovascular Disease · Diabetes · Physical Activity
Source: ClinicalTrials.gov NCT03898206 ↗
Enrolled (actual)
54
Serious AEs
0.0%
Results posted
Apr 2026
Primary outcomePrimary: Postprandial Glucose — 1.46; 1.43; 1.74; 1.53 mmol.L-1.5 h-1
Summary
The purpose of this study is to examine whether breaking up prolonged sitting with short regular bouts of walking can reduce blood sugar and cholesterol levels after eating, which are risk markers for Type 2 diabetes and heart disease. This study will compare these responses in normal-weight versus overweight/obese South Asian adults.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Postprandial Glucose |
1.46; 1.43; 1.74; 1.53 | — |
| SECONDARY Postprandial Triglycerides |
0.35; 0.23; 0.67; 0.63 | — |
| SECONDARY Postprandial Insulin |
24.69; 26.95; 44.19; 41.12 | — |
| SECONDARY Metabolic Load Index |
1.76; 1.60; 2.39; 2.17 | — |
| SECONDARY Resting Energy Expenditure |
0.22; 0.21; 0.18; 0.23 | — |
| SECONDARY Resting Fat Oxidation |
3.21; 0.67; 2.42; 2.12 | — |
| SECONDARY Resting Carbohydrate Oxidation |
44.28; 54.75; 43.57; 52.38 | — |
| SECONDARY Mean Arterial Pressure |
89.17; 87.24; 94.22; 93.33 | — |
| SECONDARY Heart Rate |
67.50; 67.62; 69.24; 69.76 | — |
Eligibility Criteria
Inclusion Criteria
- Self-identified South Asian ethnicity.
- Self-report sitting at least 7 hours per day.
- Normal weight, overweight or obese.
Exclusion Criteria
- Unable to speak and read English.
- Contraindications to performing light-intensity walking.
- Diagnosed cardiovascular disease or diabetes.
Data sourced from ClinicalTrials.gov (NCT03898206). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.