N/A
Completed N=474
Come As You Are - Assessing the Efficacy of a Nurse Case Management HIV Prevention and Care Intervention Among Homeless Youth
Behavior, Risk
Source: ClinicalTrials.gov NCT03910218 ↗
Enrolled (actual)
474
Serious AEs
1.3%
Results posted
Jun 2025
Primary outcomePrimary: Number of Participants Who Use Preventive Prophylaxis (PrEP) — 20; 18 Participants
Summary
The purpose of this study is to to determine the efficacy of the Nurse Case Management HIV (NCM4HIV) intervention on HIV prevention compared to usual care among Youth Experiencing Homelessness (YEH).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants Who Use Preventive Prophylaxis (PrEP) |
42; 12 | — |
| PRIMARY Number of Participants Who Use Non-occupational Post-exposure Prophylaxis (nPEP) |
6; 5 | — |
| PRIMARY Number of Participants Who Use Condoms at Last Sex as Measured by the Youth Risk Behavior Survey |
74; 34 | — |
| PRIMARY Number of Participants Who Tested Positive for HIV or Sexually Transmitted Infection (STI) |
38; 18 | — |
| SECONDARY Mental Health as Measured by the Brief Symptom Index-18 |
— | — |
| SECONDARY Housing Status |
69; 23; 27; 14; 19; 13 | — |
| SECONDARY Number of Participants With Substance Use as Measured by Item 11 in the Texas Christian University (TCU) Drug Screen II |
170; 79 | — |
| SECONDARY Mental Health as Measured by the Patient Health Questionnaire (PHQ-9) |
7.7; 6.6 | — |
Eligibility Criteria
Inclusion Criteria
- youth engaged in high-risk sexual activity or intravenous drug use
- speak English
- homeless
- not planning to move out of the metro area during the study
Exclusion Criteria
- youth with very low literacy
- severe acute mental symptoms
Data sourced from ClinicalTrials.gov (NCT03910218). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.