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Phase 4 Completed N=536 Health Services Research

Mail Order Mifepristone Study

Abortion Early · Pregnancy Related
Source: ClinicalTrials.gov NCT03913104 ↗
Enrolled (actual)
536
Serious AEs
0.6%
Results posted
Aug 2024
Primary outcomePrimary: Acceptability: Satisfaction With Mail-Order Dispensing of Medication Abortion — 452; 26; 7; 4 Number of abortions
◆ Published Evidence
Emerging
17citations · ~4 / year
Mail-order pharmacy dispensing of mifepristone for medication abortion after in-person clinical assessment.
Contraception · 2022 · Likely link

Summary

This study aims to evaluate the feasibility, acceptability, and effectiveness of dispensing mifepristone via a mail-order pharmacy. The investigators will recruit patients at up to 10 primary care and internal medicines sites not currently providing abortion services around the country, as well as abortion clinic sites. Patients will go through routine in clinic visits to determine eligibility and then will receive the medications in the mail at their preferred address. The investigators will survey patients 3 and 14 days after the initial clinic visit and interview providers at the end of the study.

Linked Publications (2)

  • Mail-order pharmacy dispensing of mifepristone for medication abortion after in-person clinical assessment.
    Contraception · 2022 · 17 citations · Likely link
  • Primary care and abortion provider perspectives on mail-order medication abortion: a qualitative study.
    BMC women's health · 2024 · 4 citations · Open access · Likely link

Outcome Measures

OutcomeResultp-value
PRIMARY
Acceptability: Satisfaction With Mail-Order Dispensing of Medication Abortion
452; 26; 7; 4; 6
PRIMARY
Acceptability: Would Use Mail-Order Dispensing Again
431; 20; 26
SECONDARY
Feasibility: Proportion of Patients Who Receive Medications by Day 2 and Day 3
381; 436
SECONDARY
Feasibility: Confidentiality Maintained When Receiving Medications by Mail
486; 8; 1
SECONDARY
Clinical Effectiveness of Mail-Order Medication Abortion
499; 5; 6
SECONDARY
Clinical Safety of Mail-Order Medication Abortion
21; 3; 0
SECONDARY
Provider Acceptability of Mail-Order Dispensing of Medication Abortion
24

Eligibility Criteria

Inclusion Criteria

  • Women seeking medication abortion through 63 days gestation
  • Eligible for MifeprexⓇ at a study site
  • English or Spanish speaking
  • Willing and able to participate in the study, including willing and able to receive medications at home or other preferred address within 3 days of initial medication abortion visit

Exclusion Criteria

  • Not pregnant
  • Not seeking medication abortion
  • under the age of 15
  • Over 63 days gestation
  • Contraindicated for medication abortion
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03913104) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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