N/A
N=150
Reducing Prehospital Medication Errors & Time to Drug Delivery by EMS During Simulated Pediatric CPR
Cardiopulmonary Arrest · Resuscitation · Pediatrics · Medication Errors · Emergency Medical Services
Bottom Line
View on ClinicalTrials.gov: NCT03921346 ↗Enrolled (actual)
150
Serious AEs
—
Results posted
Oct 2024
Primary outcome: Primary: Medication Dosage Errors — 5.7; 62.8 percentage of medication errors
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Mobile device app (PedAMINES™) 1st drug (Device); Mobile device app (PedAMINES™) 2nd drug (Device); Mobile device app (PedAMINES™) 3rd drug (Device); Mobile device app (PedAMINES™) 4th drug (Device); Conventional method 1st drug (Device); Conventional method 2nd drug (Device); Conventional method 3rd drug (Device); Conventional method 4th drug (Device)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Pediatric Clinical Research Platform
- Primary completion
- Jan 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Medication Dosage Errors |
5.7; 62.8 | — |
| SECONDARY Time to Drug Preparation and Time to Drug Delivery |
146.6; 186.1; 186.8; 233.3 | — |
| SECONDARY Type of Medication Errors |
17; 191; 16; 172; 0; 55 | — |
| SECONDARY Perceived Stress |
36.1; 35.4; 39.0; 49.8; 4.2; 3.9 | — |
| SECONDARY Stress Level Measured by Heart Rate Monitoring (Smartwatch). |
79.3; 78.5; 123.1; 124.1; 121.1; 119.9 | — |
| SECONDARY Unified Theory of Acceptance and Use of Technology (UTAUT) Questionnaire and System Usability Score (SUS) |
4.69; 4.61; 4.49; 4.55; 4.74; 4.14 | — |
Summary
The study investigators will recruit paramedics in many Emergency Medical Services (EMS) in Switzerland to prepare direct intravenous (IV) emergency drugs during a standardized simulation-based pediatric out-of-hospital cardiac arrest scenario. According to randomization, each paramedic will be asked to prepare sequentially 4 IV emergency drugs (epinephrine, midazolam, dextrose 10%, sodium bicarbonate 4.2%) following either their current conventional methods or by the aim of a mobile device app. This app is designed to support drug preparation at pediatric dosages. In a previous multicenter randomized trial with nurses, the investigators reported the ability of this app to significantly reduce in-hospital continuous infusion medication error rates and drug preparation time compared to conventional preparation methods during simulation-based resuscitations. In this trial, the aim was to assess this app during pediatric out-of-hospital cardiopulmonary resuscitation with paramedics.
Eligibility Criteria
Inclusion Criteria
- To be paramedic certified
- To know how to prepare direct IV drugs
- To have previously completed the 5-minute introductory course to the use of the app PedAMINES™ dispensed by the study investigators
- Participation agreement
Exclusion Criteria
- To have at any time previously used the app PedAMINES™
- To have not undergone the 5-minute introductory course to the use of the app PedAMINES™
Data sourced from ClinicalTrials.gov (NCT03921346). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.