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Phase 4 Completed N=55 Randomized Double-blind Treatment

Total Joint Arthroplasty and Sleep

Primary Total Hip Arthroplasty · Primary Total Knee Arthroplasty
Source: ClinicalTrials.gov NCT03968939 ↗
Enrolled (actual)
55
Serious AEs
0.0%
Results posted
Jul 2024
Primary outcomePrimary: Epworth Sleepiness Scale (ESS) — 7.73; 7.81; 8.36; 7.31 score on a scale
◆ Published Evidence
No publication linked

No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.

Summary

To compare non-prescription sleep aids (low-dose diphenhydramine and melatonin) to sleep hygiene education for improving postoperative sleep quality after total joint arthroplasty.

Outcome Measures

OutcomeResultp-value
PRIMARY
Epworth Sleepiness Scale (ESS)
7.73; 7.81; 8.36; 7.31; 8.17; 7.30
PRIMARY
Pittsburgh Sleep Quality Index (PSQI)
10.13; 10.96; 12.14; 9.46; 13.17; 12.55
PRIMARY
Visual Analogue Scale (VAS) for Pain
4.67; 4.46; 6.21; 4.31; 3.67; 4.09

Eligibility Criteria

Inclusion Criteria

All patients undergoing elective primary total hip or knee arthroplasty

Exclusion Criteria

  • History of substance abuse
  • Workman's compensation patients
  • Revision joint replacement
  • History of prescription or over-the- counter sleep aid use
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03968939). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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