Phase 4
Completed N=20
Intercostal Nerve Cryoablation for Postoperative Pain Management
Pain, Postoperative
Source: ClinicalTrials.gov NCT03972397 ↗
Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Nov 2023
Primary outcomePrimary: Score on Numeric Pain Scale (NPS) — 1.5; 3 score on a scale
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
The purpose of the study is to assess the efficacy of intercostal nerve cryoablation on the magnitude and duration of postoperative pain control both in patients undergoing thoracoabdominal incisions for the descending or thoracoabdominal aortic aneurysm repair.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Score on Numeric Pain Scale (NPS) |
1.5; 3 | — |
| PRIMARY Brief Pain Inventory (BPI) - Severity Score |
2; 4 | — |
| PRIMARY Brief Pain Inventory (BPI) - Pain Interference Score |
0; 0 | — |
| PRIMARY 5-point Satisfaction Scale |
5; 5 | — |
| SECONDARY Total Amount in mg of Opioid Medication Consumed |
— | — |
| SECONDARY Number of Participants Who Require of Opioids at the Time of Discharge |
— | — |
| SECONDARY Number of Participants Who Utilize Patient-controlled Analgesia (PCA) |
— | — |
| SECONDARY Amount of Patient-controlled Analgesia (PCA) Used |
— | — |
| SECONDARY Number of Participants Who Attain Physical Therapy Goal That Justifies Discharge From Inpatient Physical Therapy Within 72 Hours |
— | — |
| SECONDARY Length of Hospital Stay |
10.5; 8 | — |
| SECONDARY Hospital Cost for Patient Care During Hospitalization |
— | — |
Eligibility Criteria
Inclusion Criteria
- Descending/thoracoabdominal incision is planned
- There is reasonable expectation that the patient will be extubated within 48 hours after surgery
Exclusion Criteria
- The patient has a known allergy to morphine or any opioid
- The patient has a known chronic pain disorder or takes daily opioid medication > 1 month prior to surgery
- The surgeon/anesthesiologist concludes that the period for intubation will be likely be for more than 48 hours after surgery There is anticipated difficulty communicating pain status due to language or other barriers at the investigator discretion.
Data sourced from ClinicalTrials.gov (NCT03972397). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.