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N/A N=163 Randomized Double-blind Basic Science

Effect of Emotion Mindsets on Emotion Processing

Emotions

Enrolled (actual)
163
Serious AEs
Results posted
Apr 2025
Primary outcome: Primary: Mean Change From Pre to Post Mindset Manipulation on Emotion Mindset Scale (Measures Beliefs About Whether Emotions Are Fixed or Malleable) — 3.03; 3.03; 2.17; 2.76 score on a scale — p=<0.001

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Growth Mindset (Behavioral); Brain Education (Behavioral)
Age
Pediatric, Adult · 13+ yrs
Sex
Female
Sponsor
University of Illinois at Urbana-Champaign
Primary completion
Jun 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Mean Change From Pre to Post Mindset Manipulation on Emotion Mindset Scale (Measures Beliefs About Whether Emotions Are Fixed or Malleable)
3.03; 3.03; 2.17; 2.76 <0.001 sig
PRIMARY
Mean Change From Pre to Post Mindset Manipulation on Emotional Self-efficacy Scale (Measure Beliefs About Ability to Control Emotions)
3.53; 3.34; 3.79; 3.40 0.023 sig
PRIMARY
Mean Change From Pre to Post Mindset Manipulation on Emotional Self-efficacy Vignettes (Measure Beliefs About Ability to Control Emotions in Specific Situations)
2.89; 2.70; 3.16; 2.72 <.001 sig
PRIMARY
Mean Difference in Performance on Go/Nogo Task- Reaction Time
427.40; 433.44; 423.37; 431.78; 430.37; 434.35 0.227
PRIMARY
Mean Difference in Performance on Go/Nogo Task- Accuracy
0.63; 0.60; 0.64; 0.62; 0.65; 0.63 0.272
PRIMARY
Mean Difference in Emotion Regulation Strategies on the Emotion Regulation Strategy Scale
2.54; 2.75; 3.05; 2.71; 2.77; 2.63 0.217
PRIMARY
Mean Difference in Parameter Estimates of BOLD Signal for Amygdala Activation- Social Evaluation Task
0.04; -0.01 0.265
PRIMARY
Mean Difference in Parameter Estimates of BOLD Signal for Amygdala Activation- Go/No-go Task
0.49; 0.49 0.96
PRIMARY
Mean Difference in Parameter Estimates of BOLD Signal for Frontal Parietal Network-Amygdala Connectivity- Social Evaluation Task
0.01; -0.01 0.76
PRIMARY
Mean Difference in Parameter Estimates of BOLD Signal for Frontal Parietal Network-Amygdala Connectivity- Go/No-go Task
-0.17; 0.01 .048 sig
PRIMARY
Mean Change on Self-Reported State Negative Affect
6.93; 8.00; 15.05; 16.51 0.833
PRIMARY
Mean Difference on Self-Reported Affect on Social Evaluation Task
4.34; 4.28; 1.61; 1.61; 3.49; 3.45 0.321
SECONDARY
Mean Change From Baseline to 2 Months in Emotion Mindset Scale Scores
3.03; 3.03; 2.74; 3.17 0.002 sig
SECONDARY
Mean Change From Baseline to 4 Months in Emotion Mindset Scores
3.03; 3.03; 2.80; 3.11 .033 sig
SECONDARY
Mean Change From Baseline to 2 Months in Emotional Self-efficacy Scale Scores (Measure Beliefs About Ability to Control Emotions)
3.64; 3.38; 3.55; 3.40 0.403
SECONDARY
Mean Change From Baseline to 4 Months in Emotional Self-efficacy Scale Scores (Measure Beliefs About Ability to Control Emotions)
3.64; 3.37; 3.63; 3.39 0.784
SECONDARY
Mean Change From Baseline to 2 Months in Emotional Self-efficacy Vignettes Scores
2.95; 2.70; 2.93; 2.69 0.916
SECONDARY
Mean Change From Baseline to 4 Months in Emotional Self-efficacy Vignettes Scores
2.95; 2.71; 3.19; 2.74 0.048 sig
SECONDARY
Mean Change From Baseline to 2 Months in Self-Reported Emotion Regulation Strategies Scores
2.97; 2.69; 3.07; 2.85; 2.40; 2.45 0.566
SECONDARY
Mean Change From Baseline to 4 Months in Self-Reported Emotion Regulation Strategies Scores
2.96; 2.73; 3.12; 2.78; 2.42; 2.49 0.363

Summary

The guiding scientific premise for this research is that a growth emotion mindset will promote more adaptive emotion processing than a fixed emotion mindset. Because emotional sensitivity is particularly salient in adolescent girls, we will focus on this group. Using an experimental design, adolescent girls will be randomly assigned to either a mindset manipulation or a control group (brain education). Each group will complete a 25-minute computer-based lesson followed by a social stressor and a functional magnetic resonance imaging session. Two specific aims will be addressed: (1) to determine whether a growth mindset induction, relative to a control condition, predicts more adaptive emotion processing at the neural, behavioral, and psychological levels of processing; and (2) to determine whether neural processing of emotion accounts for the effect of a growth emotion mindset manipulation on behavioral and psychological processing of emotion. This study builds on a strong empirical database establishing the effect of mindsets on multiple domains of functioning but will be the first to examine the implications of a growth vs. fixed mindset about emotion for emotion processing in adolescent girls, thereby elucidating one specific youth attribute that can support or disrupt emotional development.

Eligibility Criteria

Inclusion Criteria

  • Female age 13-18 years old
  • Over-sample (approximately 1/3 of sample) for score >= .75 standard deviation (SD) on a screening measure of fixed mindset about emotion
  • English-speaking
  • Ability to independently complete tasks and measures

Exclusion Criteria

  • History of surgery involving metal implants
  • Possible metal fragments in the eyes or other parts of body
  • Pacemaker
  • A history of claustrophobia
  • Braces
  • Weighing over 250 pounds
  • Pregnancy or possibility of being pregnant
  • Severe medical conditions (e.g., blind or deaf, head trauma)
  • Learning disability or other condition that interferes with ability to complete tasks
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03978871). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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