N/A N=25

Correlation of Several Formulas to Evaluate Insulin Sensitivity With the Predicted M Index

Healthy Lifestyle

Bottom Line

View on ClinicalTrials.gov: NCT04010370 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Dec 2020

Primary outcome: Primary: Insulin Sensitivity With PREDIM (PREDIcted M) Index — 72.48 index

Study Design & Population

Study type: Observational
Phase: N/A
Interventions: —
Age: Adult · 30+ yrs
Sex: All
Sponsor: University of Guadalajara
Primary completion: Feb 2020

Outcome Measures

Outcome	Result	p-value
PRIMARY Insulin Sensitivity With PREDIM (PREDIcted M) Index	72.48	—
PRIMARY Insulin Sensitivity With McAuley Index	46.69	<0.001 sig
PRIMARY Insulin Sensitivity With Belfiore Index	1.52	0.319
PRIMARY Insulin Sensitivity With Cederholm Index	153.25	0.27
PRIMARY Insulin Sensitivity With Avignon Index	271.11	0.246
PRIMARY Insulin Sensitivity With Matsuda Index	8.15	0.259
PRIMARY Insulin Sensitivity With Gutt Index	79.99	0.69
PRIMARY Insulin Sensitivity With Stumvoll Index	0.1339	0.022 sig
PRIMARY Insulin Sensitivity With HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) Index	1.61	0.69
PRIMARY Insulin Sensitivity With ISI (Insulin Sensitivity Index) Index	18.61	0.69
PRIMARY Insulin Sensitivity With Raynaud Index	6.05	0.541
PRIMARY Insulin Sensitivity With QUICKI (The Quantitative Insulin Sensitivity Check Index) Index	0.36	0.69
PRIMARY Insulin Sensitivity With FIRI (Fasting Insulin Resistance Index) Index	26.13	0.531
PRIMARY Insulin Sensitivity With Bennett Index	0.64	0.726
PRIMARY Insulin Sensitivity With TyG (Triglycerides and Glucose Index) Index	1.88	0.787

Summary

Recently, an index based on the oral insulin sensitivity index with glucose (OGIS) has been proposed in combination with anthropometric variables, called PREDIcted M (PREDIM), however, there is no evidence of the correlation of this with respect to the various indices (McAuley, Belfiore, Cederholm, Avignon, Matsuda, Gutt, Stumvoll, HOMA-IR (Homeostatic Model Assessment for Insulin Resistance), ISI (Insulin Sensitivity Index), Raynaud, QUICKI (The quantitative insulin sensitivity check index), FIRI (Fasting Insulin Resistance Index), Bennett, TyG (triglycerides and glucose index)) in healthy patients.

Eligibility Criteria

Inclusion Criteria

Both genres
Age 30 to 60 years
BMI 120/80 mmHg
Glucose >100 mg/dL
Postprandial glucose >140 mg/dL
Cholesterol >200 mg/dL
Triglycerides >150 mg/dL
Smoking
Women with polycystic ovarian syndrome
History of metabolic, cardiovascular, thyroid, renal, pancreatic and/or arterial hypertension
Use of medications that modify insulin sensitivity (corticosteroids)
Previous surgery or infection
Symptoms of vomiting and/or excessive nausea

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04010370). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.