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N/A N=73 Randomized Double-blind Treatment

Total Knee Replacement With Tourniquet or Aquamantys

Knee Replacement

Enrolled (actual)
73
Serious AEs
0.0%
Results posted
Apr 2024
Primary outcome: Primary: Isometric Quadriceps Strength — 11.58; 9.60 Nm/kg

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Aquamantys (Device); Tourniquet (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Stephen Duncan
Primary completion
Feb 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Isometric Quadriceps Strength
SECONDARY
Pain (VAS)
SECONDARY
Knee Osteoarthritis (KOOS,JR)
13; 10; 16; 17
SECONDARY
Emotional Health (VR-12 MCS)
SECONDARY
Knee Function Questionnaire
SECONDARY
Sit to Stand Test
SECONDARY
Opioid Use
SECONDARY
Isometric Quadriceps Strength

Summary

The purpose of this study is to compare quadriceps muscle strength, pain, opioid consumption and patient function during the first three months after short-stay total knee replacement between patients treated with short-duration tourniquet knee replacement with the Aquamantys® bipolar sealer versus those treated with the standard of care (tourniquet used throughout the case and no Aquamantys®). By doing this study, investigators hope to learn if short duration tourniquet knee replacement with the Aquamantys® bipolar sealer is more effective than standard of care (tourniquet used throughout the case and no Aquamantys®). The purpose of this study is to compare quadriceps muscle strength, pain, opioid consumption and patient function during the first three months after short-stay total knee replacement between patients treated with short-duration tourniquet knee replacement with the Aquamantys® bipolar sealer versus those treated with the standard of care (tourniquet used throughout the case and no Aquamantys®).

Eligibility Criteria

Inclusion Criteria

  • primary total knee arthroplasty

Exclusion Criteria

  • repeat knee replacement (revision arthroplasty)
  • bilateral knee replacements on the same day
  • partial knee replacements
  • health or social limitations that do not allow for the participant to be discharged to home on the same day or day after surgery.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04016285). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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