Phase 4
N=31
ProvodineTM Decreases Hand Contamination
Hand Hygiene
Bottom Line
View on ClinicalTrials.gov: NCT04023682 ↗Enrolled (actual)
31
Serious AEs
0.0%
Results posted
Aug 2021
Primary outcome: Primary: Control Period-Count the Number of Baseline Colony Forming Units Cultured From Anesthesiologist's Hands — 589.3 Colony forming units
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 4
- Interventions
- Provodine Hand Sanitizer (Drug)
- Age
- Adult, Older Adult · 22+ yrs
- Sex
- All
- Sponsor
- Sundara Reddy
- Primary completion
- Nov 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Control Period-Count the Number of Baseline Colony Forming Units Cultured From Anesthesiologist's Hands |
589.3 | — |
| PRIMARY Intervention Period-Count the Number of Baseline Colony Forming Units Cultured From Anesthesiologist's Hands |
788.9 | — |
| SECONDARY Control Phase-Count and Compare the Number of CFU's After the First Case of the Day. |
825.2 | — |
| SECONDARY Interventional Phase-Count and Compare the Number of CFU's After the First Case of the Day. |
248.9 | — |
| SECONDARY Control Phase-Count and Compare the Number of CFU's After the Second Case of the Day. |
971.2 | — |
| SECONDARY Interventional Phase-Count and Compare the Number of CFU's After the Second Case of the Day. |
382.2 | — |
| SECONDARY Number of Providers/Participants Who Acquired a Pathogen or Commensal During the Day. |
11; 2; 3; 3; 3 | — |
Summary
The purpose of this study is to see whether Provodine, an FDA approved product, provides long-lasting protection on the hands of staff who provide anesthesia for patients. If this product does provide long-lasting protection, it could be used for hand hygiene in the operating room and it could help prevent infections after operations. Fifteen anesthesia providers (15 main operating room [MOR] and 5 ambulatory surgery center [ASC]) who agree to participate will participate in the pre-intervention and intervention periods. During the pre-intervention or baseline period, the investigators will do bag broth cultures of anesthesia providers' hands just before the start of their first case of the day . The participants will then rinse and dry their hands to remove the culture medium. The investigators will also obtain cultures after the first case of the day, and after the second case. During the intervention period (ProvodineTM; usual hand hygiene practice), the investigators obtain hand cultures from the same anesthesia providers at the beginning of the day. The participants will then then do a hand scrub with ProvodineTM. The investigators will obtain a second hand culture at this point and participants will rinse and dry their hands to remove the culture medium and then apply a small amount of ProvodineTM as a hand rub. The investigators will obtain cultures after the first case of the day, and after the second case of the day. If participants are still providing anesthesia to their second case 6 hours after they applied ProvodineTM, the participants will apply a small of ProvodineTM amount as a hand rub at this time.
For anesthesia providers in the ASC, the investigators will use the same protocol with the following exception. Because cases are likely to be shorter, the investigators will obtain the final cultures after the last case of the day or after the case that ends closest to 6 hours after ProvodineTM was applied in the morning.
Eligibility Criteria
Inclusion Criteria
- Must be an anesthesia provider at The University of Iowa Hospitals and Clinics
Exclusion Criteria
- Are not an anesthesia provider at The University of Iowa Hospitals and Clinics
Data sourced from ClinicalTrials.gov (NCT04023682). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.