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Phase 4 N=31 Prevention

ProvodineTM Decreases Hand Contamination

Hand Hygiene

Enrolled (actual)
31
Serious AEs
0.0%
Results posted
Aug 2021
Primary outcome: Primary: Control Period-Count the Number of Baseline Colony Forming Units Cultured From Anesthesiologist's Hands — 589.3 Colony forming units

Study Design & Population

Study type
Interventional
Phase
Phase 4
Interventions
Provodine Hand Sanitizer (Drug)
Age
Adult, Older Adult · 22+ yrs
Sex
All
Sponsor
Sundara Reddy
Primary completion
Nov 2014

Outcome Measures

OutcomeResultp-value
PRIMARY
Control Period-Count the Number of Baseline Colony Forming Units Cultured From Anesthesiologist's Hands
589.3
PRIMARY
Intervention Period-Count the Number of Baseline Colony Forming Units Cultured From Anesthesiologist's Hands
788.9
SECONDARY
Control Phase-Count and Compare the Number of CFU's After the First Case of the Day.
825.2
SECONDARY
Interventional Phase-Count and Compare the Number of CFU's After the First Case of the Day.
248.9
SECONDARY
Control Phase-Count and Compare the Number of CFU's After the Second Case of the Day.
971.2
SECONDARY
Interventional Phase-Count and Compare the Number of CFU's After the Second Case of the Day.
382.2
SECONDARY
Number of Providers/Participants Who Acquired a Pathogen or Commensal During the Day.
11; 2; 3; 3; 3

Summary

The purpose of this study is to see whether Provodine, an FDA approved product, provides long-lasting protection on the hands of staff who provide anesthesia for patients. If this product does provide long-lasting protection, it could be used for hand hygiene in the operating room and it could help prevent infections after operations. Fifteen anesthesia providers (15 main operating room [MOR] and 5 ambulatory surgery center [ASC]) who agree to participate will participate in the pre-intervention and intervention periods. During the pre-intervention or baseline period, the investigators will do bag broth cultures of anesthesia providers' hands just before the start of their first case of the day . The participants will then rinse and dry their hands to remove the culture medium. The investigators will also obtain cultures after the first case of the day, and after the second case. During the intervention period (ProvodineTM; usual hand hygiene practice), the investigators obtain hand cultures from the same anesthesia providers at the beginning of the day. The participants will then then do a hand scrub with ProvodineTM. The investigators will obtain a second hand culture at this point and participants will rinse and dry their hands to remove the culture medium and then apply a small amount of ProvodineTM as a hand rub. The investigators will obtain cultures after the first case of the day, and after the second case of the day. If participants are still providing anesthesia to their second case 6 hours after they applied ProvodineTM, the participants will apply a small of ProvodineTM amount as a hand rub at this time. For anesthesia providers in the ASC, the investigators will use the same protocol with the following exception. Because cases are likely to be shorter, the investigators will obtain the final cultures after the last case of the day or after the case that ends closest to 6 hours after ProvodineTM was applied in the morning.

Eligibility Criteria

Inclusion Criteria

  • Must be an anesthesia provider at The University of Iowa Hospitals and Clinics

Exclusion Criteria

  • Are not an anesthesia provider at The University of Iowa Hospitals and Clinics
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04023682). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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