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N/A Completed N=8 Supportive Care

Uphill Walking as Exercise for COPD Patients

Source: ClinicalTrials.gov NCT04026529 ↗
Enrolled (actual)
8
Serious AEs
0.0%
Results posted
Aug 2024
Primary outcomePrimary: Dyspnea — 9.62; 9.12 score on a scale

Summary

This study is designed to provide preliminary information regarding how to improve pulmonary rehabilitation for persons with chronic obstructive pulmonary disease (COPD). Pulmonary rehabilitation is an exercise program for COPD patients that is recommended and benefits some, but not all, patients. The question being studied in this trial is whether walking on an incline might be better than walking on faster on a flat surface in training muscles so that patients might be less short of breath with exercise.

Outcome Measures

OutcomeResultp-value
PRIMARY
Dyspnea
9.62; 9.12

Eligibility Criteria

Inclusion Criteria

  • Veterans from all sex/gender, race, and ethnicity will be recruited
  • All subjects will undergo post-bronchodilator spirometry and be clinically stable
  • All subjects must have documented FEV1/FVC ratio of <0.7, and between 30% to 80% FEV1% predicted
  • If subjects have non-qualifying spirometry, they will not be screened further
  • Subjects with qualifying spirometry will be screened further
  • Potential subjects must have a BMI of less than 35 kg/m2 and must be free from co-morbidities that may affect walking patterns
  • e.g., peripheral arterial disease, diabetes, low back pain

Exclusion Criteria

  • Confounding effects such as neurological, musculoskeletal, or metabolic disease
  • Subjects taking medications that alter mood or metabolic demand will be excluded
  • All potential subjects must be cleared for participation by a physician after undergoing a cardiopulmonary exercise test
  • Require an O2 mask during rest or activity
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04026529). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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