N/A N=93 Randomized Triple-blind Prevention

Neuroplastic Mechanisms Underlying Augmented Neuromuscular Training

Anterior Cruciate Ligament Injuries

Bottom Line

View on ClinicalTrials.gov: NCT04069520 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jul 2024

Primary outcome: Primary: Neural Mechanisms for Injury-resistant Movement Pattern Acquisition — 0.28; 0.26; 0.26; 0.21 % BOLD Signal change

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: aNMT Biofeedback (Other); Sham Biofeedback (Other)
Age: Pediatric, Adult · 12+ yrs
Sex: Female
Sponsor: Emory University
Primary completion: Aug 2021

Outcome Measures

Outcome	Result	p-value
PRIMARY Neural Mechanisms for Injury-resistant Movement Pattern Acquisition	0.28; 0.26; 0.26; 0.21	—
PRIMARY Knee Joint Biomechanics During Landing Task	83.49; 80.50; 86.06; 83.48	—
SECONDARY Neural Mechanisms for Injury-resistant Movement Pattern Transfer to VR-simulated Sport	0.31; 0.26; 0.26; 0.31	—
SECONDARY Knee Joint Biomechanics During VR-simulated Sport	68.43; 68.93; 73.27; 71.89	—

Summary

The purpose of this study is to determine the neural mechanisms of augmented neuromuscular training (aNMT). Participants will complete a 6-week course of neuromuscular training with either aNMT biofeedback or sham biofeedback. An MRI will be performed before and after the training program.

Eligibility Criteria

Inclusion Criteria

enrolled in parent study "Real-time Sensorimotor Feedback for Injury Prevention Assessed in Virtual Reality"

Exclusion Criteria

contraindications to MRI scan

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04069520). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.