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N/A Completed N=50 Other

The First Puncture Success Rate of a Novel Injeq IQ-Tip™ System in Pediatric Lumbar Punctures

Lumbar Puncture
Source: ClinicalTrials.gov NCT04070144 ↗
Enrolled (actual)
50
Serious AEs
0.0%
Results posted
Jun 2023
Primary outcomePrimary: The First Puncture Success Rate — 79.5 percentage of procedures

Summary

The investigation aims to demonstrate the first puncture success rate, as proxy of clinical benefit and clinical performance, of bioimpedance spectroscopy based spinal needle guidance method among pediatric hemato-oncology patients requiring lumbar punctures.

Outcome Measures

OutcomeResultp-value
PRIMARY
The First Puncture Success Rate
79.5
PRIMARY
Rate of Serious Adverse Events
SECONDARY
Percentage of Procedures With Post-dural Puncture Headache (PDPH)
6
SECONDARY
Percentage of CSF Samples With Greater or Equal to 10 Erythrocytes / mm^3
17.3
SECONDARY
Percentage of Procedures With Other Complications or Adverse Events
15; 14; 14; 7
SECONDARY
Aggregate Sensitivity of CSF Detection
86.1
SECONDARY
Aggregate False Detection Rate of CSF Detection
9.2
SECONDARY
Number of Required Attempts Per Successful Lumbar Puncture Procedure
1.3
SECONDARY
Number of Failed Lumbar Puncture Procedures
1

Eligibility Criteria

Inclusion Criteria

  • Pediatric hemato-oncology patients whose diagnosis or treatment plan requires lumbar puncture to acquire a CSF sample or to inject drug or other substance
  • Written and signed informed consent before the procedure from the parent and/or patient depending on the age of the patient

Exclusion Criteria

  • Parents and/or patient refusal to participate or parents and/or patient unable to give informed consent
  • Any contraindications to a lumbar puncture. Contraindications include skin infection around the puncture area, unstable hemodynamics, bleeding tendency and increased intracranial pressure
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04070144). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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