N/A
N=19
Heart at Work Study
Occupational Diseases · Cardiovascular Diseases · Cardiovascular Risk Factor · Occupational Exposure
Bottom Line
View on ClinicalTrials.gov: NCT04075279 ↗Enrolled (actual)
19
Serious AEs
0.0%
Results posted
May 2021
Primary outcome: Primary: 24-hour Heart Rate — 83.8; 78.5 beats per minute
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Adult · 35+ yrs
- Sex
- Male
- Sponsor
- University of Pittsburgh
- Primary completion
- Apr 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY 24-hour Heart Rate |
83.8; 78.5 | — |
| SECONDARY 24-hour Ambulatory Systolic Blood Pressure |
126.0; 124.0 | — |
| SECONDARY Nocturnal Heart Rate Variability, RMSSD |
34.17; 35.34 | — |
| SECONDARY Physical Activity Pattern. Steps Per Day |
12,772; 7,923 | — |
| SECONDARY Nocturnal Heart Rate Variability, SDNN |
39.85; 42.14 | — |
| SECONDARY Nocturnal Heart Rate Variability, LF |
6.18; 6.45 | — |
| SECONDARY Nocturnal Heart Rate Variability, HF |
5.22; 5.56 | — |
| SECONDARY Physical Activity Pattern. MVPA |
72.4; 41.5 | — |
| SECONDARY Physical Activity Pattern. LPA |
391.5; 285.2 | — |
| SECONDARY Physical Activity Pattern. Sedentary |
492.5; 629.7 | — |
| SECONDARY Physical Activity Pattern. Upright |
462.4; 325.2 | — |
| SECONDARY 24-hour Ambulatory Diastolic Blood Pressure |
75.2; 72.6 | — |
Summary
This is an observational study to examine the cardiovascular mechanisms of increased cardiovascular mortality in those with high activity occupations.
Eligibility Criteria
Inclusion Criteria
- middle age (35-59 years)
- male
- self-report working full-time in the food service industry (≥30 hours/week)
- self-report predominantly completing light intensity activity job responsibilities (≥75% work time walking, light movement, or standing)
Exclusion Criteria
- Resting blood pressure of ≥150 mmHg systolic and/or ≥95 mmHg diastolic
- currently taking medications that are known to affect blood pressure or heart rate (e.g. Beta-blockers, ACE inhibitors, etc.)
- greater than low risk to participate in physical activity as determined by PAR-Q (answer of yes to any of the 7 physical activity readiness questionnaire questions)
- report working a second job in addition to their primary full-time job
- report working overnight shifts (10pm-6am)
- reported physical dysfunction (inability to walk 2 city blocks or climb 2 flights of stairs)
- inability to complete the sub-maximal exercise test to completion (80% age-predicted heart rate maximum)
- Currently being treated for a serious medical condition such as kidney disease, liver disease, cancer, or heart disease.
Data sourced from ClinicalTrials.gov (NCT04075279). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.