N/A N=1,422 Randomized Double-blind Screening

Digital Outreach Intervention for Lung Cancer Screening

Lung Cancer

Bottom Line

View on ClinicalTrials.gov: NCT04083859 ↗

Enrolled (actual)

1,422

Serious AEs

0.0%

Results posted

Jan 2025

Primary outcome: Primary: Number of Participants With Electronic Health Record-verified Completion of a Chest CT Scan — 164; 113 Participants

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: mPATH-Lung (Other); Lung health video (Other)
Age: Adult, Older Adult · 50+ yrs
Sex: All
Sponsor: Wake Forest University Health Sciences
Primary completion: Sep 2023

Outcome Measures

Outcome	Result	p-value
PRIMARY Number of Participants With Electronic Health Record-verified Completion of a Chest CT Scan	164; 113	—
SECONDARY LCS Screening Decision	—	—
SECONDARY Proportion of Patients With LCS Clinic Visits Scheduled	—	—
SECONDARY Proportion of Patients With LCS Clinic Visits Completed	—	—
SECONDARY Proportion of Patients With LCS Scans Ordered	—	—
SECONDARY LCS Clinic Referral Requested Through mPATH	—	—
SECONDARY Lung Cancer Screening Test Results	—	—
SECONDARY Number of LCS False Positives	—	—
SECONDARY Invasive Procedures Following LCS Scan	—	—
SECONDARY Proportion of Patients With Complications Following LCS	—	—
SECONDARY Number of Diagnosed Lung Cancers	—	—
SECONDARY How Diagnosed Lung Cancers Were Detected	—	—
SECONDARY Stage of Lung Cancers Diagnosed	—	—
SECONDARY Overscreening	—	—
SECONDARY Reach of Digital Outreach Strategy	3267	—
SECONDARY Completion of mPATH-Lung Program	—	—

Summary

mPATH-Lung (mobile Patient Technology for Health - Lung) is an innovative digital outreach program that identifies patients who qualify for lung cancer screening and helps them get screened. The study will: 1) Determine the effect of mPATH-Lung on receipt of lung cancer screening in a pragmatic randomized-controlled trial conducted with primary care patients in two large health networks, 2) Elucidate the drivers of patients' screening decisions and screening behavior; and 3) Explore implementation outcomes that will impact the sustainability and dissemination of mPATH-Lung using program data, surveys, and interviews. This project will determine how mPATH-Lung affects patients' screening decisions and their completion of screening.

Eligibility Criteria

Inclusion Criteria

Meet the Medicare criteria for lung cancer screening, as updated in February 2022:
Age 50 - 77 years
Smoked at least 20 pack years
Current smoker or quit smoking within the past 15 years
Be scheduled to see a primary care provider within the health network in the next 3-4 weeks
Have a patient portal account or cellphone number listed in the electronic health record

Exclusion Criteria

Patients flagged as needing a language interpreter in the electronic health record (electronic messages and intervention is delivered in English only).
Those for whom lung cancer screening would be inappropriate:
Prior history of lung cancer
Chest CT within the last 12 months
Those with medical conditions predicting shorter life expectancy
Patients whose home address is not within the state of North Carolina. (Due to telehealth guidelines)

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04083859). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.