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N/A N=372 Randomized Supportive Care

Health Information Technology System ("Roadmap 2.0") in the Context of Hematopoietic Cell Transplantation

Hematologic Diseases

Enrolled (actual)
372
Serious AEs
0.0%
Results posted
Apr 2026
Primary outcome: Primary: Caregiver Health-related Quality of Life (HRQOL) Assessed by the PROMIS Global Health Scale. — 48.18; 48.16 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Wearable activity sensor (Other); Roadmap 2.0 information system (Behavioral); Survey administration (Other); Roadmap 2.0 information system with Positive Activities (Behavioral)
Age
Pediatric, Adult, Older Adult · 5+ yrs
Sex
All
Sponsor
University of Michigan Rogel Cancer Center
Primary completion
Aug 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Caregiver Health-related Quality of Life (HRQOL) Assessed by the PROMIS Global Health Scale.
48.18; 48.16

Summary

The purpose of this research study is to measure the effects of using a mobile phone app (Roadmap 2.0) on the health-related quality of life of caregivers and patients undergoing allogeneic/autologous hematopoietic cell transplantation (HCT).

Eligibility Criteria

Inclusion Criteria

  • The caregiver must have an eligible patient (see below)
  • The caregiver must be of age ≥18 years.
  • The caregiver should be comfortable in reading and speaking English and signing informed consents.
  • The caregiver should provide at least 50% of care needs.
  • An eligible patient is one who identifies the eligible caregiver as their primary caregiver (i.e., provides at least 50% of care needs).
  • An eligible patient is age ≥5 years.
  • An eligible patient is scheduled to undergo HCT.
  • An eligible patient is able to sign informed consent/assent forms.
  • Patients and caregivers agree to provide informed consent that is in regulatory compliance and IRBMED-approved and also in accordance to institutional guidelines. A patient is able to undergo HCT at the U-M only if a designated family caregiver (e.g., parents, adult children, spouses, family members, neighbors, friends) accepts the roles, in accordance to the Clinical Practice Guidelines of the U-M BMT Program.
  • The caregiver and patient must have his/her own smartphone to participate.

Exclusion Criteria

  • Patient does not meet eligibility criteria to undergo HCT at the U-M BMT Program or Oregon Health & Sciences University.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04094844). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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