N/A
N=56
Effect of Chewing Gum in Hemodialysis Patients
Chewing Gum · Hemodialysis
Bottom Line
View on ClinicalTrials.gov: NCT04142216 ↗Enrolled (actual)
56
Serious AEs
—
Results posted
May 2020
Primary outcome: Primary: Change From Baseline Intradialytic Weight Gain — 2.53; 2.44 kg
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Chewing Gum (Dietary_supplement)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Istanbul Demiroglu Bilim University
- Primary completion
- Jan 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change From Baseline Intradialytic Weight Gain |
2.53; 2.44 | — |
| PRIMARY Change From Baseline Feeling of Thirst at Three Months |
5.04; 1.72 | — |
| PRIMARY Change From Baseline Dry Mouth at Three Months |
5.04; 1.72 | — |
| PRIMARY Change From Baseline Dry Mouth at Three Months |
5.04; 1.72 | — |
| PRIMARY Change From Baseline Intradialytic Symptoms at Three Months |
19.13; 19.18 | — |
| SECONDARY Change From Baseline Anxiety at Three Months |
8.18; 8.40 | — |
| SECONDARY Change From Baseline Fluid Control at Three Months |
53.95; 58.04 | — |
| SECONDARY Change From Baseline Depression at Three Months |
8.63; 8.13 | — |
Summary
The aim of this prospective randomized controlled study was to investigate the effects of chewing gum on interdialytic weight gain, thirst, dry mouth and intradialytic symptoms in hemodialysis patients.
Eligibility Criteria
Inclusion Criteria
- 18 years of age or older
- On maintenance hemodialysis three times per week for four hours per session
- Receiving hemodialysis therapy for a least six moths at the time of the study
- Able to communicate in Turkish
- Willing to participate to the study
Exclusion Criteria
- 18 years of age younger
- Absence of psychiatric disorders that cause cognitive dysfunction, such as Alzheimer's disease or chronic psychosis.
- The patient who took chemotherapy and radiotherapy
- Have salivary gland infection and dementia
- Oral and / or dental diseases to prevent chewing gum
- Unwilling to to participate to the study
Data sourced from ClinicalTrials.gov (NCT04142216). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.