N/A
N=3,245
Persuasion in Medicine: Experimental Evidence on Sender and Signal Effects
Flu, Human · Influenza, Human · Covid19
Bottom Line
View on ClinicalTrials.gov: NCT04160975 ↗Enrolled (actual)
3,245
Serious AEs
0.0%
Results posted
Jun 2021
Primary outcome: Primary: Rating of Sender — .1828917; -.0750636; .0997998; -.5397662 index
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Video about safety and effectiveness of adult seasonal flu vaccination (Behavioral)
- Age
- Adult · 18+ yrs
- Sex
- Male
- Sponsor
- Harvard University
- Primary completion
- Feb 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Rating of Sender |
.1828917; -.0750636; .0997998; -.5397662 | — |
| PRIMARY Rating of Signal |
.1387205; -.0088105; .1423725; -.0806321 | — |
| PRIMARY Signal Content Recall |
-.0062555; .0193832; .0041984; .1166304 | — |
| PRIMARY Safety Beliefs |
-.0979564; -.027714; -.1065867; -.0242752 | — |
| PRIMARY Coupon Interest |
-.0078177; -.0827849; .0280955; -.0162865 | — |
| PRIMARY (Posterior) Flu Vaccine Intent |
.0263281; .0034755; .0268659; .0187403 | — |
| PRIMARY COVID-19 Vaccine Intent |
.0350147; .009072; .0544277; .0881949 | — |
| PRIMARY Flu Vaccine Take-up |
-7.70997; -01.39307; -12.00413; 14.96955 | — |
Summary
The aim of the study is to identify what sender/signal combinations are most persuasive in encouraging low socioeconomic males living in the U.S. to take-up seasonal flu vaccination. The investigators plan to recruit male subjects and randomly assign them to four persuasion treatments: three of which vary dimensions of the sender of a medical recommendation (racial concordance and authority treatments) and one which varies the signal (standard vs. empathetic). Specifically, the investigators will show subjects videos of either Black or white actors/actresses providing scripted information on the flu vaccination. The investigators will randomize the race of the sender and if the subject is Black, also randomize the authority of the sender, with the actor portraying either a doctor or a layperson. In addition, the investigators will vary the script used in the experiment between one that acknowledges past injustices (indicated as an empathetic script hereafter) and one that does not (indicated as a standard script hereafter). The investigators will provide subjects a free flu shot coupon and elicit the price at which subjects would be willing to give up this coupon for a cash reward. Lastly, in light of the relevance of vaccination take-up in combating COVID-19 pandemic, the investigators will assess demand for information about a COVID-19 vaccine, with subjects invited to receive results of a safety and efficacy review from a trusted or standard source. The design requires the collection of baseline and endline surveys combined with administrative data from pharmacies about coupon redemption. The primary outcomes of interest are posterior beliefs about seasonal flu vaccination, demand and willingness-to-pay (WTP) for a free flu shot coupon, redemption of the coupon, and demand for information about a COVID-19 vaccine.
Eligibility Criteria
Inclusion Criteria
- Age: See above.
- Education: Less than a college degree.
- Gender: Male.
- Race: Caucasian or African American.
- Miscellaneous: Has not received the flu shot in the current flu season yet.
- Miscellaneous: Has sound on his device turned on.
Exclusion Criteria
- Fast survey-taking: subjects who are among the 5% fastest in terms of total time spent on survey within race and treatment group.
- Nonsense answers (those that do not have decipherable English) in the open text sections that suggest low effort.
- Inconsistent responses to questions (such as being willing to give up $10 to receive a flu coupon but not $1).
- Repeat survey takers as indicated by duplicate emails or IP addresses in survey data.
Data sourced from ClinicalTrials.gov (NCT04160975). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.