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N/A N=3,245 Randomized Double-blind Health Services Research

Persuasion in Medicine: Experimental Evidence on Sender and Signal Effects

Flu, Human · Influenza, Human · Covid19

Enrolled (actual)
3,245
Serious AEs
0.0%
Results posted
Jun 2021
Primary outcome: Primary: Rating of Sender — .1828917; -.0750636; .0997998; -.5397662 index

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Video about safety and effectiveness of adult seasonal flu vaccination (Behavioral)
Age
Adult · 18+ yrs
Sex
Male
Sponsor
Harvard University
Primary completion
Feb 2021

Outcome Measures

OutcomeResultp-value
PRIMARY
Rating of Sender
.1828917; -.0750636; .0997998; -.5397662
PRIMARY
Rating of Signal
.1387205; -.0088105; .1423725; -.0806321
PRIMARY
Signal Content Recall
-.0062555; .0193832; .0041984; .1166304
PRIMARY
Safety Beliefs
-.0979564; -.027714; -.1065867; -.0242752
PRIMARY
Coupon Interest
-.0078177; -.0827849; .0280955; -.0162865
PRIMARY
(Posterior) Flu Vaccine Intent
.0263281; .0034755; .0268659; .0187403
PRIMARY
COVID-19 Vaccine Intent
.0350147; .009072; .0544277; .0881949
PRIMARY
Flu Vaccine Take-up
-7.70997; -01.39307; -12.00413; 14.96955

Summary

The aim of the study is to identify what sender/signal combinations are most persuasive in encouraging low socioeconomic males living in the U.S. to take-up seasonal flu vaccination. The investigators plan to recruit male subjects and randomly assign them to four persuasion treatments: three of which vary dimensions of the sender of a medical recommendation (racial concordance and authority treatments) and one which varies the signal (standard vs. empathetic). Specifically, the investigators will show subjects videos of either Black or white actors/actresses providing scripted information on the flu vaccination. The investigators will randomize the race of the sender and if the subject is Black, also randomize the authority of the sender, with the actor portraying either a doctor or a layperson. In addition, the investigators will vary the script used in the experiment between one that acknowledges past injustices (indicated as an empathetic script hereafter) and one that does not (indicated as a standard script hereafter). The investigators will provide subjects a free flu shot coupon and elicit the price at which subjects would be willing to give up this coupon for a cash reward. Lastly, in light of the relevance of vaccination take-up in combating COVID-19 pandemic, the investigators will assess demand for information about a COVID-19 vaccine, with subjects invited to receive results of a safety and efficacy review from a trusted or standard source. The design requires the collection of baseline and endline surveys combined with administrative data from pharmacies about coupon redemption. The primary outcomes of interest are posterior beliefs about seasonal flu vaccination, demand and willingness-to-pay (WTP) for a free flu shot coupon, redemption of the coupon, and demand for information about a COVID-19 vaccine.

Eligibility Criteria

Inclusion Criteria

  • Age: See above.
  • Education: Less than a college degree.
  • Gender: Male.
  • Race: Caucasian or African American.
  • Miscellaneous: Has not received the flu shot in the current flu season yet.
  • Miscellaneous: Has sound on his device turned on.

Exclusion Criteria

  • Fast survey-taking: subjects who are among the 5% fastest in terms of total time spent on survey within race and treatment group.
  • Nonsense answers (those that do not have decipherable English) in the open text sections that suggest low effort.
  • Inconsistent responses to questions (such as being willing to give up $10 to receive a flu coupon but not $1).
  • Repeat survey takers as indicated by duplicate emails or IP addresses in survey data.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04160975). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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