N/A
N=213
Inpatient Cognitive-Behavioral Therapy to Reduce Suicide Risk Post-Discharge
Suicide, Attempted
Bottom Line
View on ClinicalTrials.gov: NCT04168645 ↗Enrolled (actual)
213
Serious AEs
34.3%
Results posted
Apr 2025
Primary outcome: Primary: Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors — 1; 1; 0; 0 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Cognitive Behavioral Therapy (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Hartford Hospital
- Primary completion
- Aug 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors |
1; 1; 0; 0; 1; 4 | — |
| PRIMARY Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors |
0.00; 0.00; 0.00; 0.00; 0.00; 0.00 | — |
| PRIMARY The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe |
31; 21; 20; 15; 7; 16 | — |
| PRIMARY Columbia Suicide Severity Rating Scale Suicidal Ideation Intensity Scale Total Score |
6.04; 9.68; 6.84; 10.29; 4.76; 7.79 | — |
| PRIMARY Number of Participants With Readmissions |
5; 8; 2; 3; 7; 5 | — |
Summary
The goal of this randomized-controlled trial is to determine whether adding brief cognitive-behavioral therapy for suicide prevention (BCBT) to inpatient treatment improves suicide-related outcomes after the person leaves the hospital. The study will also determine whether being diagnosed with a substance use disorder impacts these outcomes. Participants will either receive treatment as usual or treatment as usual plus up to four sessions of BCBT during their inpatient stay. They will complete monthly follow-up assessments for six months after leaving the hospital.
Eligibility Criteria
Inclusion Criteria
- Any Gender
- Age 18-65 inclusive
- Fluent in English (speaking, reading, and writing)
- Having made a suicide attempt within one week preceding admission or suicidal ideation and plan on admissions along with suicide attempt within previous two years. Admission will be defined as admission to either the medical floor (in cases where medical stabilization is required prior to transfer to psychiatric inpatient facility) or to psychiatric inpatient facility (in cases where medical stabilization is not required). A suicide attempt will be defined as behavior that is self-directed and deliberately results in injury or the potential for injury to oneself for which there is evidence, whether explicit or implicit, of intent to die.
Exclusion Criteria
- Age <18 or ≥66 years old
- History of schizophrenia or schizoaffective disorder
- History of intellectual disability or organic brain illness
- Active mania or other psychiatric or medical condition that would preclude informed consent or participation in the trial, in the investigator's opinion
- ECT included on patient's inpatient treatment plan. Patients who are referred for ECT after starting the study will be withdrawn from the study.
- Discharge expected within four business days of attending approval.
Data sourced from ClinicalTrials.gov (NCT04168645). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.