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Phase 4 N=104 Randomized Treatment

Comparing the Effectiveness of Individual vs. Household Treatment for Scabies in Lambaréné, Gabon

Scabies · Households

Enrolled (actual)
104
Serious AEs
0.0%
Results posted
Nov 2020
Primary outcome: Primary: Number of Participants With Clinical Cure — 20; 33 Participants

Study Design & Population

Study type
Interventional
Phase
Phase 4
Interventions
Benzyl Benzoate 25% Topical Application Lotion (Drug)
Age
Pediatric, Adult, Older Adult
Sex
All
Sponsor
Centre de Recherche Médicale de Lambaréné
Primary completion
Feb 2019

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants With Clinical Cure
20; 33
SECONDARY
Proportion of Affected Household Members Per Household

Summary

It is unclear whether individual treatment of scabies is similarly effective compared to household treatment. This study therefore compares these two treatment strategies with topical benzyl benzoate for treating scabies in Lambaréné and surroundings in Gabon. Subjects presenting with uncomplicated scabies are randomized into either the Individual Treatment group, where only the affected subjects receive treatment, or the Household Treatment group, where all family members are treated in parallel to the affected subjects regardless of signs and symptoms. The primary endpoint is clinical cure after 28 days; the secondary endpoint is the proportion of affected household members per household after 28 days.

Eligibility Criteria

Inclusion Criteria

  • diagnosed with active, uncomplicated scabies
  • no known hypersensitivity or allergy against benzyl benzoate

Exclusion Criteria

  • hypersensitivity or allergy against benzyl benzoate
  • severe superinfection of scabies lesions
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04205669). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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