N/A
N=40
The Acute Effect of Vaping on Food Intake
Energy Intake · Food Intake · E-Cig Use · Appetite
Bottom Line
View on ClinicalTrials.gov: NCT04219189 ↗Enrolled (actual)
40
Serious AEs
0.0%
Results posted
Nov 2023
Primary outcome: Primary: Energy Intake — 1102.1; 1003.4; 910.4; 868.3 Kilocalories
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Vaping condition (Other); Control condition (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Virginia Commonwealth University
- Primary completion
- Sep 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Energy Intake |
1102.1; 1003.4; 910.4; 868.3 | — |
| SECONDARY Dietary Added Sugar Intake |
28.4; 43.0; 25.0; 37.7 | — |
| SECONDARY Dietary Sugar Intake |
32.9; 54.0; 29.2; 50.0 | — |
| SECONDARY Dietary Fat Intake |
40.9; 52.9; 37.7; 51.2 | — |
| SECONDARY Dietary Carbohydrate Intake |
82.2; 106.6; 72.8; 105.3 | — |
| SECONDARY Dietary Protein Intake |
51.7; 58.3; 46.7; 53.1 | — |
| SECONDARY Dietary Calcium Intake |
287.1; 404.5; 294.4; 404.2 | — |
| SECONDARY Dietary Cholesterol Intake |
121.0; 143.2; 113.1; 146.3 | — |
| SECONDARY Dietary Fiber Intake |
3.2; 4.4; 3.2; 4.9 | — |
| SECONDARY Dietary Iron Intake |
2.9; 3.3; 2.5; 3.5 | — |
| SECONDARY Dietary Potassium Intake |
606.4; 739.1; 544.4; 808.6 | — |
| SECONDARY Dietary Sodium Intake |
2045.5; 2350.4; 1865.3; 2255.8 | — |
| SECONDARY Dietary Saturated Fat Intake |
14.5; 19.5; 13.6; 18.4 | — |
| SECONDARY Dietary Vitamin D Intake |
0.16; 0.25; 0.16; 0.25 | — |
| SECONDARY Difference in Food Cravings |
49.8; 48.7; 46.5; 52.2 | — |
Summary
This study assesses the acute effects of a standardized 20-minute vaping episode compared to a non-vaping control condition on ad libitum food intake during a 30-minute buffet meal, occurring approximately 45 minutes after the vaping episode
Eligibility Criteria
Inclusion Criteria
- 18 - 65 years of age (ID card verified)
- Reports either everyday e-cigarette use with liquid containing at least 0.3% (~3 mg/ml) nicotine or some day e-cigarette use ( at least 3 days a week) with liquid containing at least 3% (~30 mg/ml) nicotine for the past 30 days.
Exclusion Criteria
- being unwilling to consume the foods provided due to: a) dietary limitations or preferences or b) allergies to the foods provided.
- being unwilling to take 20 puffs from a JUUL device containing a 5% nicotine pod
- self-reported current, diagnosed medical condition(s) will be excluded automatically: heart-related conditions (e.g., recent heart attack/stroke, coronary heart disease), severe immune system disorders (e.g., HIV/AIDS, multiple sclerosis), respiratory disorders (e.g., COPD, asthma), kidney diseases, liver diseases (e.g., cirrhosis), or seizures
- observed high blood pressure at screening (systolic >140; diastolic >90)
- other self-reported current, diagnosed medical conditions (e.g., specific food allergies, diabetes, thyroid disease, lyme disease) will be considered for exclusion after consultation with the PI and medical monitor
- self-reported current, diagnosed psychiatric conditions or who report current psychiatric treatment or psychotropic medication use
- past month use of cocaine, opioids, benzodiazepines, methamphetamine, or other (non-cannabis) illicit drugs
- self-report of >25 days out of the past 30 for alcohol use or >20 days out of the past 30 for cannabis use.
- women who are breast-feeding or test positive for pregnancy (by urinalysis at screening)
- women using progestin-IUDS for birth control
- women using birth control injections (e.g., Depo-Provera)
- women who received a hysterectomy and still have ovaries present
- self-report intending to quit tobacco/nicotine products in the next 30 days
Data sourced from ClinicalTrials.gov (NCT04219189). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.