N/A N=508 Screening

Enhancing Cancer Prevention and Control Pathways-Native Health Initiative

Cancer, Breast · Cancer, Colon · Cancer, Cervix

Bottom Line

View on ClinicalTrials.gov: NCT04259762 ↗

Enrolled (actual)

508

Serious AEs

0.0%

Results posted

Sep 2025

Primary outcome: Primary: Aim 3, Focus Groups, Descriptive: Knowledge, Barriers and Support, and Communication About Breast, Cervix, and Colorectal Cancers — 85; 85; 85; 85 Participants

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Aim 8 (INT, Pilot Test): Breast, Colorectal, and Cervical Cancer Screening Cognitive-Behavioral Interventions (Other)
Age: Adult, Older Adult · 21+ yrs
Sex: All
Sponsor: New Mexico Cancer Research Alliance
Primary completion: Oct 2023

Outcome Measures

Outcome	Result	p-value
PRIMARY Aim 3, Focus Groups, Descriptive: Knowledge, Barriers and Support, and Communication About Breast, Cervix, and Colorectal Cancers	85; 85; 85; 85; 11; 85	—
PRIMARY Aim 4, Community Survey, Descriptive: Cancer Control Needs	95; 92; 129	—
PRIMARY Aim 8, INT, Pilot Test: Age/Gender-specific Breast, Colorectal, and Cervical Cancer Screening	20; 28; 11; 15; 26; 23	—

Summary

There are continued disparities in cancer incidence, mortality, and survival between American Indians (AIs) and Whites on cancers responsive to early screening (i.e., breast, colorectal, and cervical) in the US. In New Mexico (NM), AIs compared with other racial/ethnic populations are significantly less likely to adhere to recommended screening guidelines. The purpose of this trial is to develop and pilot test multilevel/multicomponent intervention strategies to enhance screening for breast, colorectal, and cervical cancers.

Eligibility Criteria

Inclusion Criteria: Breast Cancer Screening Intervention

Women age 45-75
Average risk for breast cancer
Never had a mammogram OR not had a mammogram within the past 2 years
Residing in the Zuni Pueblo

Exclusion Criteria: Breast Cancer Screening Intervention. Meeting at least one of the following criteria:

Women with breast implants, pregnant, or breast feeding
History of breast cancer
Have new breast complaints such as lump or nipple discharge

Inclusion Criteria: Colorectal Cancer Screening Intervention

Men and women aged 45-75
Average risk for colorectal cancer
Never had a fecal occult blood test (FOBT), or fecal immunochemical test (FIT) or a colonoscopy OR not had a FOBT or FIT in the past year, OR no colonoscopy in the past 10 years
Residing in the Zuni Pueblo

Exclusion Criteria: Colorectal Cancer Screening Intervention. Meeting at least one of the following criteria:

History of colorectal cancer, total colectomy, adenomatous polyps, or inflammatory bowel disease
Up-to-date with colorectal cancer screening
Severe comorbidity
Incarceration
Family history of colorectal cancer
Hospice/terminal care status

Inclusion Criteria: Cervical Cancer Screening Intervention

Women aged 21-65
Never had a cytology (Pap smear) OR had a Pap smear more than 3 years ago OR women aged 30-75, and never had screening with a combination of cytology and human papillomavirus testing OR no combination of testing in the past 5 years
Residing in the Zuni Pueblo

Exclusion Criteria: Cervical Cancer Screening Intervention. Meeting at least one of the following criteria:

History of total hysterectomy
High risk for cervical cancer due to suppressed immune system (e.g., HIV infection, organ transplant, long-term steroid use)
Women over age 65 who have had regular screenings with normal results

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04259762). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.