N/A
N=47
Post-Operative Cognitive Dysfunction in Normal Aging Patients Undergoing Elective Orthopedic Surgery
Post Operative Cognitive Dysfunction
Bottom Line
View on ClinicalTrials.gov: NCT04267328 ↗Enrolled (actual)
47
Serious AEs
0.0%
Results posted
Apr 2024
Primary outcome: Primary: Presence of Post Operative Cognitive Dysfunction (POCD) — 15 Participants
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Elective Orthopedic Surgery (Procedure)
- Age
- Adult, Older Adult · 50+ yrs
- Sex
- All
- Sponsor
- HealthPartners Institute
- Primary completion
- May 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Presence of Post Operative Cognitive Dysfunction (POCD) |
15 | — |
Summary
Post-operative cognitive dysfunction (POCD) is a common concern for aging patients undergoing elective orthopedic surgery and significantly effects health outcomes. This study aims to evaluate the incidence of and risk factors associated with post-operative cognitive dysfunction in aging patients without prior history for mild cognitive impairment or dementia.
Eligibility Criteria
Inclusion Criteria
- Age ≥50 and ≤90
- Any patient undergoing elective orthopedic surgery for hip, knee, or shoulder replacement (as defined by diagnostic codes: M16.0, M16.12, M16.11, M17.0, M17.12, M17.11, M19.011, M19.012)
Exclusion Criteria
- History of cognitive impairment of dementia
- Montreal cognitive assessment (MoCA) <26
- History of Parkinson's disease, progressive supranuclear palsy, corticobasal degeneration, normal pressure hydrocephalus, Huntington's disease, stroke, seizure disorder, brain tumor, or brain surgery
- History of surgery requiring anesthesia within the past 3 months
Data sourced from ClinicalTrials.gov (NCT04267328). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.