N/A
Completed N=34
Quantifying Energetic Demands of Walking for People With Cerebral Palsy
Source: ClinicalTrials.gov NCT04303078 ↗Enrolled (actual)
34
Serious AEs
0.0%
Results posted
Jan 2026
Primary outcomePrimary: Net Nondimensional Oxygen Cost — -34.13; -15.86; 1.07; -0.60 Percent change relative to baseline
Summary
The purpose of this study is to examine the underlying mechanisms that contribute to high energy costs for people with cerebral palsy (CP) as they walk.
The investigators will characterize the cost landscape of children with CP, quantifying the magnitude of cost (net nondimensional oxygen consumption) associated with walking and common sub-tasks of walking, such as supporting and stabilizing the body.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Net Nondimensional Oxygen Cost |
-34.13; -15.86; 1.07; -0.60 | — |
| SECONDARY Three-dimensional Gait Kinematics (Baseline) |
21.6; 13.6; 23.4; 16.2; 24.3; 13.2 | — |
| SECONDARY Three-dimensional Gait Kinematics (Support) |
22.1; 18.0; 23.0; 16.4; 21.5; 15.4 | — |
| SECONDARY Three-dimensional Gait Kinetics (Baseline) |
0.462; 0.604; 0.447; 0.613; 0.160; 0.321 | — |
| SECONDARY Three-dimensional Gait Kinetics (Support) |
0.269; 0.312; 0.465; 0.559; 0.103; 0.177 | — |
| SECONDARY Passive Joint Range of Motion |
51.478; 34.000; -0.435; -4.700; 3.174; 0.000 | — |
| SECONDARY Selective Motor Control |
1.348; 2.000; 1.826; 2.000; 1.870; 2.000 | — |
| SECONDARY Lower Extremity Strength |
4.391; 5.000; 3.652; 5.000; 4.913; 5.000 | — |
Eligibility Criteria
Inclusion Criteria for Cases:
- 8-17 years old
- Diagnosed with bilateral cerebral palsy
- Gross Motor Function Classification System II
- No surgery within the last 9 months
- No current baclofen pump or explantation in the last 2 months
- No botulinum toxin or phenol injections in the last 2 months
- Had a prior gait and motion analysis at Gillette Children's Specialty Healthcare
- Participant and caregiver able to speak and read English
- Ability to follow instructions
Inclusion Criteria for Controls:
- 8-17 years old
- Participant and caregiver able to speak and read English
- Ability to follow instructions
Data sourced from ClinicalTrials.gov (NCT04303078). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.