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N/A N=269 Randomized Basic Science

Does Social Buffering Continue to be Effective Over the Peripubertal Period When Friends Share the Stressor Experience?

Adolescent Behavior · Social Stress

Enrolled (actual)
269
Serious AEs
0.0%
Results posted
Feb 2025
Primary outcome: Primary: Cortisol AUCi — 0.0043; 0.0256; 0.0177; 0.022 (ug/dl)*minutes

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Friend and target (Other); Friend support (Other); unfamiliar peer and target (Other); alone (Other)
Age
Pediatric · 11+ yrs
Sex
All
Sponsor
University of Minnesota
Primary completion
Jun 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Cortisol AUCi
0.0043; 0.0256; 0.0177; 0.022
PRIMARY
sAA AUCi
0.0364; 0.0434; 0.0021; 0.0255
SECONDARY
Self Report of Stress
1.65; 1.6; 1.65; 1.79

Summary

The purpose of this experiment is to determine whether social buffering by friends of stress physiology remains effective later in puberty when friends share the load versus when they provide support but are not undergoing the stressor with the target child. There are four conditions: (1) Friend and Target both undergo the stressor, (2) Friend provides support but does not undergo the stressor, (3) Unfamiliar Peer and Target undergo the stressor, and (4) Alone (no partner).

Eligibility Criteria

Inclusion Criteria

  • sufficient vision, hearing, and language skills to provide verbal and written assent
  • ability to see and read stimuli presented on the computer screen
  • ability to hear verbal instructions provided by the experimenter and judges

Exclusion Criteria

  • premature birth (less than 37 weeks)
  • congenital and/or chromosomal disorders (e.g. cerebral palsy, FAS, mental retardation, Turner Syndrome, Down Syndrome, Fragile X)
  • Autism Spectrum Disorders
  • history of serious medical illness (e.g., cancer, organ transplant)
  • serious psychiatric illness
  • systemic glucocorticoids or beta-adrenergic medication use
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04311996). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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