N/A N=18 Randomized Double-blind Other

Impacts of a Combined Berry Extract Supplement on Vascular Function and Oxygen Utility Capacity in Young Adults

Healthy

Bottom Line

View on ClinicalTrials.gov: NCT04312022 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Feb 2024

Primary outcome: Primary: Endothelial Function — 11.7; 8.2 percent dilation

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Berry extract (Dietary_supplement); Placebo (Other)
Age: Adult · 19+ yrs
Sex: All
Sponsor: University of Nebraska
Primary completion: Mar 2019

Outcome Measures

Outcome	Result	p-value
PRIMARY Endothelial Function	11.7; 8.2	—
SECONDARY Systolic Blood Pressure	110.0; 112.5	—
SECONDARY Diastolic Blood Pressure	72.8; 72.4	—
SECONDARY Oxygen Utility Capacity (Tissue Saturation Index)	71.5; 64.3	—
SECONDARY Exercise Fatigue Index During Leg Extension	27.4; 25.0	—
SECONDARY Exercise Fatigue Index During Leg Flexion	24.9; 24.8	—
SECONDARY Plasma Total Antioxidant Capacity	15.8; 15.0	—
SECONDARY Oxygenated Hemoglobin	10.1; 9.6	—
SECONDARY Deoxygenated Hemoglobin	-0.4; -2.7	—

Summary

The purpose of this study is to investigate the impacts of a combined berry extract supplement (hawthorn berry, tart cherry, and bromelain extracts) on total antioxidant capacity, endothelial function, blood pressure, oxygen utility capacity, and fatigue index in healthy young adults.

Eligibility Criteria

Inclusion Criteria

otherwise healthy adult

Exclusion Criteria

cardiovascular disease
neurological disorder
metabolic disorder
respiratory disorder
renal diseases
musculoskeletal injury
bleeding disorder
allergy to fruit
pregnant/breast feeding
taking daily medication (prescription or over-the-counter)

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04312022). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.