N/A N=55 Randomized Double-blind Other

Visual and Electromyography Assessments in Response to Train-of-Four Stimulation of the Ulnar Nerve

Residual Neuromuscular Blockade

Bottom Line

View on ClinicalTrials.gov: NCT04352127 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

May 2022

Primary outcome: Primary: Subjective Evaluation to Neurostimulation — 48.2; 44.8 percentage of evaluations

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: TetraGraph (Device)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Mayo Clinic
Primary completion: Jun 2021

Outcome Measures

Outcome	Result	p-value
PRIMARY Subjective Evaluation to Neurostimulation	48.2; 44.8	—
SECONDARY Incidence of Residual Neuromuscular Blockade	1; 0	—

Summary

Researchers are comparing the accuracy of measuring muscle relaxation during and after surgery with a device that provides numeric value versus visual observation to count of muscle twitches or absence of them by a medical provider monitoring your anesthesia during surgery.

Eligibility Criteria

Inclusion Criteria

Age > or = 18 years old
Patients willing to participate and provide an informed consent
Patients undergoing an elective surgical procedure that requires use of NMBA agents administered intraoperatively.

Exclusion Criteria

Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury.
Patients with systemic neuromuscular diseases such as myasthenia gravis
Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents, i.e., severe renal impairment or end-stage liver disease.
Patients having surgery that would involve prepping the arm or leg into the sterile field

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04352127). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.