N/A
Completed N=72
Using Technology-Assisted Stepped Care Intervention to Improve Adherence in Adolescents With Asthma
Source: ClinicalTrials.gov NCT04365556 ↗Enrolled (actual)
72
Serious AEs
0.0%
Results posted
Sep 2025
Primary outcomePrimary: Percent Change in Inhaler Adherence Via Electronic Monitoring — 14.05; 13.43 percent — p=<0.001
Summary
To test the preliminary efficacy of the TASC adherence promotion intervention for adolescents with asthma in a feasibility randomized controlled trial compared to treatment as usual control arm.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percent Change in Inhaler Adherence Via Electronic Monitoring |
14.05; 13.43 | <0.001 sig |
| SECONDARY Change in Composite Asthma Severity Index |
-0.92; -0.34 | 0.69 |
| SECONDARY Feasibility Questionnaire |
4.30 | — |
| SECONDARY Usability: Questionnaire |
75.83 | — |
Eligibility Criteria
Inclusion Criteria
- Patient age between 12-18 years
- Patient is diagnosed with severe-persistent or moderate-persistent asthma per NAEPP asthma guidelines
- Patient is prescribed at least one daily inhaled controller medication or a daily combination inhaled corticosteroid and long-acting beta-agonist and a beta-agonist bronchodilator
- English fluency for patient, caregiver, and clinician
Exclusion Criteria
- Significant cognitive deficits that may interfere with comprehension per medical team or chart review
- Diagnosis of serious mental illness (e.g., schizophrenia)
- Diagnosis of pervasive developmental disorder
- Active chronic disease apart from asthma or allergic disease (e.g. Bronchiectasis, pulmonary hypertension, and moderate or severe tracheomalacia)
- Patient receives school administered daily controller medication at the time of the enrollment visit
Data sourced from ClinicalTrials.gov (NCT04365556). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.