N/A
N=20
Patient-Derived Organoids for Rectal Cancer
Rectum Cancer
Bottom Line
View on ClinicalTrials.gov: NCT04371198 ↗Enrolled (actual)
20
Serious AEs
—
Results posted
Aug 2023
Primary outcome: Primary: Number of Participants With Biopsies That Form Spherical Organoids — 14 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Biopsy (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Duke University
- Primary completion
- Aug 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With Biopsies That Form Spherical Organoids |
14 | — |
Summary
The purpose of this study is to determine the feasibility of establishing patient-derived organoids from pre-treatment rectal adenocarcinoma biopsies.
Eligibility Criteria
Inclusion
- Age ≥18 years old.
- Able to provide informed consent.
- Undergoing proctoscopy.
Exclusion
- Patient not planned to receive neoadjuvant radiotherapy
Data sourced from ClinicalTrials.gov (NCT04371198). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.