N/A
N=78
iTransition Development
Human Immunodeficiency Virus · HIV Seropositivity
Bottom Line
View on ClinicalTrials.gov: NCT04383223 ↗Enrolled (actual)
78
Serious AEs
0.0%
Results posted
Aug 2025
Primary outcome: Primary: Linkage to Adult Care — 16; 22; 0; 0 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- iTransition (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Emory University
- Primary completion
- Jun 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Linkage to Adult Care |
16; 22; 0; 0 | — |
| SECONDARY Care Retention Per Each 6-month Period |
17; 27; 0; 0; 14; 31 | — |
| SECONDARY Number of Participants With Viral Suppression |
10; 26; 0; 0 | — |
Summary
Youth living with HIV are at high risk of falling out of care when they transition from pediatric to adult care. The investigators are proposing to develop a mobile app to help both clinical providers and patients navigate this process.
Eligibility Criteria
Inclusion Criteria
For YLH Historical Control Group
- YLH (regardless of gender/assigned sex at birth) age ≥ 18 years;
- Has plan for HCT within next 6 months;
- Enrolled in care at Grady IDP pediatric/adolescent clinic or CHOP AI/SI clinics.
For YLH iTransition Intervention Group
- YLH (regardless of gender/assigned sex at birth) age ≥ 18 years;
- Has plan for HCT within next 6 months;
- Enrolled in care at Grady IDP pediatric/adolescent clinic or CHOP AI/SI clinics;
- Owns a smartphone and/or tablet
- Reports consistent internet access (defined as no lapse >24 hours in last 6 months) via their smartphone or tablet.
For Provider Group
- Staff member at Grady IDP (pediatric/adolescent clinic, adult women's clinic, and/or adult men's clinic), CHOP AI/SI clinics, UPHS: HUP or Presby infectious disease clinics;
- Works with transitioning YLH;
- Access to internet via any device (e.g., smartphone, tablet, computer);
- Endorse participation in the HCT process.
For Transition Champion Group
- Staff member at Grady IDP (pediatric/adolescent clinic, adult women's clinic, and/or adult men's clinic), CHOP AI/SI clinics, UPHS: HUP or Presby infectious disease clinics;
- Works with transitioning YLH;
- Endorse participation in the HCT process;
- Access to internet via any device (e.g., smartphone, tablet, computer);
- Nominated by clinic staff where employed to be iTransition intervention point person (champion).
Exclusion Criteria For YLH Historical Control Group
- Youth who are 24 hrs in the last three months);
- Presence of serious psychiatric symptoms (e.g., active hallucinations, thought disorder) that would impair the individual's ability to provide true informed consent or participate in the study activities;
- Visibly distraught (e.g., suicidal, homicidal, exhibiting violent behavior) at the time of consent.
For Provider Group
- Not a staff member at Grady IDP, CHOP SI/AI, UPHS: HUP or Presby infectious disease clinics;
- Does not work with transitioning YLH;
- Does not have access to internet via any device (e.g., smartphone, tablet, computer).
For Transition Champion Group
- Not a staff member at Grady IDP, CHOP SI/AI, UPHS: HUP or Presby infectious disease clinics;
- Does not work with transitioning YLH;
- Does not have access to internet via any device (e.g., smartphone, tablet, computer).
Data sourced from ClinicalTrials.gov (NCT04383223). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.