N/A
N=2,596
Pragmatic Trial of Messaging to Providers About Treatment of Hyperlipidemia (PROMPT-LIPID)
High Risk Atherosclerotic Cardiovascular Disease
Bottom Line
View on ClinicalTrials.gov: NCT04394715 ↗Enrolled (actual)
2,596
Serious AEs
0.0%
Results posted
Sep 2024
Primary outcome: Primary: Proportion of Patients With Intensification of Lipid Lowering Therapy — 159; 142 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Electronic Alert (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Yale University
- Primary completion
- Jun 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Proportion of Patients With Intensification of Lipid Lowering Therapy |
159; 142 | — |
| SECONDARY Achieved LDL-C at 6 Months |
83; 83 | — |
| SECONDARY Proportion of Patients With an LDL-C of Less Than 70 mg/dL |
115; 133 | — |
| SECONDARY Proportion of Patients With an LDL-C of Less Than 55 mg/dL |
45; 53 | — |
Summary
This study is designed to evaluate the efficacy of automated electronic alerts in the electronic health record to improve rates of best practices in the treatment of patients with hyperlipidemia who present in the setting of outpatient primary care and family medicine practices within the Yale New Haven Health System.
Eligibility Criteria
Inclusion Criteria for Patient Subjects:
- Adults 18 years of age or greater
- Currently being seen as an outpatient of Internal Medicine or Cardiology within the Yale New Haven Health System
- At very high risk for ASCVD, defined by a history of a major ASCVD event, and most recent lipid profile with LDL-C greater than 70 mg/dL, with or without other high-risk features (diabetes, CKD, age >65 years)
Exclusion Criteria for Patient Subjects:
- Heart transplant recipient
- Left ventricular assist device recipient
- Hospital inpatient status
- Pregnancy
- Have opted out of clinical research in MyChart
Inclusion Criteria for Provider Subjects:
- Practicing at an outpatient cardiology or internal medicine practice with the Yale New Haven Health System
- High frequency of eligible patients seen, based on retrospective review of outpatient records
Data sourced from ClinicalTrials.gov (NCT04394715). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.