N/A N=240 Randomized Prevention

Antibiotic Selection Using Next Generation Sequencing vs Urine Culture

Kidney Stone · Renal Stone · Infection, Bacterial

Bottom Line

View on ClinicalTrials.gov: NCT04404855 ↗

Enrolled (actual)

240

Serious AEs

0.0%

Results posted

Mar 2024

Primary outcome: Primary: Incidence of Infection Post Surgery — 0; 7 participants

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: NGS + Antibiotic Recommendation (Other); Standard of Care treatment (Procedure)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: The University of Texas Health Science Center at San Antonio
Primary completion: Jan 2022

Outcome Measures

Outcome	Result	p-value
PRIMARY Incidence of Infection Post Surgery	0; 7	—
SECONDARY Number of Participants for Whom Additional Antibiotics Were Selected	3; 0	—

Summary

This is a randomized controlled clinical study evaluating the use of next-generation sequencing (NGS) to improve antibiotic prescribing before ureteroscopy or percutaneous nephrolithotomy.

Eligibility Criteria

Inclusion Criteria

Patients planning to undergo kidney or bladder stone removal surgery using endoscopy including ureteroscopy and percutaneous nephrolithotomy or any other transurethral procedure
Age 18 or older
Able to give informed consent

Exclusion Criteria

Unwilling or unable to provide informed consent
Age < 18
Does not meet inclusion criteria

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04404855). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.