N/A
N=10
Sensory Training for Visual Motion Sickness
Dizziness · Vertigo · Motion Sickness
Bottom Line
View on ClinicalTrials.gov: NCT04420949 ↗Enrolled (actual)
10
Serious AEs
0.0%
Results posted
Jan 2023
Primary outcome: Primary: Rod and Disk Test (RDT) Mean Performance — 17; 13.3; 7.8; 12.1 degrees
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Sensory re-weighting (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Wisconsin, Madison
- Primary completion
- Jun 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Rod and Disk Test (RDT) Mean Performance |
17; 13.3; 7.8; 12.1; 12.4; 10.3 | — |
| PRIMARY Multisensory Balance Evaluation (MBE) as Measured by the Intersection Point Height |
0.5; 0.53; 0.42; 0.52; 0.37; 0.39 | — |
| PRIMARY Subjective Visual Vertical (SVV) Mean Performance |
-1.34; -1.3; -1.14; -1.4; -.21; -1.96 | — |
| PRIMARY Rod and Frame Test (RFT) Mean Performance |
3.9; 7.9; 5.7; 7.2; 5.6; 8.2 | — |
| SECONDARY Vision-related Dizziness Questionnaire (VRDQ) Total Score |
0; 90.8; 0; 86; 0; 74 | — |
| SECONDARY Dizziness Handicap Inventory (DHI) Total Score |
0.4; 19.2; 0.4; 24.4; 1; 23 | — |
Summary
This is a preliminary study to determine the reliability and validity of new tests of orientation and balance, as well as to test the effects of a new treatment for visually induced dizziness. Tests involve determining vertical alignment. The treatment is task-based and involves focusing attention on internal body sensations to help improve the sense of upright. Testing is done twice before and twice after treatment, which is provided twice-weekly during a three-week period between testing. The total time participants are involved in the study is approximately six weeks.
Eligibility Criteria
Healthy Participants:
Inclusion Criteria: Participants must
- have normal self-reported cognitive function
- speak English fluently
- weigh less than 225 pounds and be less than 6'4"
- be able to support their body weight in an upright posture for 15 minutes at a time
- be able to follow the guidelines regarding permitted and prohibited additional treatments outlined in this protocol
Exclusion Criteria: Participants must not
- be pregnant or planning to become pregnant while in "on study" status
- have best-corrected visual acuity > 20/70
- have a self-reported, uncompensated, binocular vision abnormality, such as strabismus, amblyopia, or diplopia
- have peripheral neuropathy
- have a self-reported history of frequent syncope (>1/month)
Participants with Visually-induced Dizziness:
Inclusion Criteria: Participants must
- have self-reported symptoms of visually-induced dizziness
- have normal self-reported cognitive function
- speak English fluently
- weigh less than 225 pounds and be less than 6'4"
- be able to support their body weight in an upright posture for 15 minutes at a time
- be able to follow the guidelines regarding permitted and prohibited additional treatments outlined in this protocol
Exclusion Criteria: Participants must not
- be participating in vestibular and balance rehabilitation therapy and/or be pregnant or planning to become pregnant while in "on study" status
- have best-corrected visual acuity > 20/70
- have a self-reported, uncompensated, binocular vision abnormality, such as strabismus, amblyopia, or diplopia
- have peripheral neuropathy, and/or 5) have a self-reported history of frequent syncope (>1/month)
Data sourced from ClinicalTrials.gov (NCT04420949). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.