N/A N=40 Randomized Treatment

AQI and Childhood Asthma: an Intervention

Asthma · Asthma in Children

Bottom Line

View on ClinicalTrials.gov: NCT04454125 ↗

Enrolled (actual)

Serious AEs

7.5%

Results posted

Aug 2023

Primary outcome: Primary: Number of Participants With at Least One Moderate or Severe Asthma Exacerbation Over Time — 5; 4; 13; 12 Participants — p=0.32

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: AQI intervention (Behavioral); Routine care (Other)
Age: Pediatric · 8+ yrs
Sex: All
Sponsor: University of Pittsburgh
Primary completion: Mar 2021

Outcome Measures

Outcome	Result	p-value
PRIMARY Number of Participants With at Least One Moderate or Severe Asthma Exacerbation Over Time	5; 4; 13; 12	0.32
PRIMARY Mean Change in Asthma Control Over Time	0.17; 2.02; -0.31; 3.96	0.80
PRIMARY Mean Change in Pediatric Asthma Quality of Life Over Time	0.25; 0.54	0.11
SECONDARY Number of Participants Who Reported Checking the AQI Prior to Going Outside to be Active	3; 12	0.87
SECONDARY Number of Participated Who Reported Outdoor Activity Behavioral Change in Response to the AQI	2; 7	0.15
SECONDARY Number of Participants Who Reported Moderate or Vigorous Physical Activity for at Least 10 Minutes Continuously Outside in a Typical Week	9; 7	0.004 sig

Summary

This is a small pilot prospective intervention trial in children with asthma who will be randomized to receive either (A) Air Quality Index (AQI) education + an asthma action plan (control) or (B) AQI education + an asthma action plan which contains AQI behavioral recommendations + demonstrate ability to navigate to AirNow either online or on smartphone app (intervention).

Eligibility Criteria

Inclusion Criteria

Child Inclusion criteria includes:
physician diagnosis of persistent asthma- either mild, moderate, or severe;
family home internet access and/or smartphone access + willingness to download AirNow app on phone;
age 8-17 years.

Parent/guardian inclusion: parent or guardian of the child participant, of whom has met inclusion criteria.

Exclusion Criteria

Child exclusion criteria includes:
diagnosis of other chronic respiratory disease (e.g. cystic fibrosis, bronchopulmonary dysplasia, etc)
immunodeficiency- acquired or congenital
neuromuscular disease
disability affecting ambulation
cyanotic congenital heart disease
only 1 child per household eligible
no plans to leave Pittsburgh area in next 6 months

Parental/guardian exclusion criteria: none.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04454125). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.