N/A
N=57
Improving Uptake of Genetic Cancer Risk Assessment in African American Women- Video
Breast Cancer
Bottom Line
View on ClinicalTrials.gov: NCT04476654 ↗Enrolled (actual)
57
Serious AEs
—
Results posted
Oct 2024
Primary outcome: Primary: Rate of Genetic Counseling and Testing Uptake. — 18; 15; 7; 12 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- YouTube Video Arm (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- Female
- Sponsor
- Virginia Commonwealth University
- Primary completion
- Jun 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Rate of Genetic Counseling and Testing Uptake. |
18; 15; 7; 12 | — |
| SECONDARY Knowledge Scale - Genetic Counseling and Testing Knowledge . |
7.79; 8.11; 7.69; 7.50 | — |
| SECONDARY Self-efficacy Scale |
14.76; 14.21; 14.38; 14.29 | — |
Summary
Genetic counseling and testing (GCT) provides invaluable information for women who are at-risk of hereditary breast and/or ovarian cancer (HBOC). Black women underutilize GCT compared to White women. This study will conduct a RCT to test the efficacy of a culturally-tailored theory-based video intervention aimed to address key psychosocial factors (emotions, ambivalence) to improve uptake of genetic counseling in Black women at increased risk of HBOC. Findings from this study may offer an opportunity to engage at-risk Black women regarding genetic counseling through a multi-center trial and ultimately address the disparity in genetic counseling uptake that exists between Black and White women.
Eligibility Criteria
Inclusion Criteria
- Must be at least 18 years of age
- Must be at high risk for hereditary breast or ovarian cancer
- Must identify as Black/African American
- Must be a woman
- Referred to a genetic counselor for the purpose of being high risk of carrying a hereditary breast and/or ovarian cancer mutation
Genetic Counselors:
- Must be at least 18 years of age
- Must be qualified
- Must be approved by the PI
Exclusion Criteria
- Under the age of 18
- Race other than Black/African American
- Do not gave a high risk for hereditary breast or ovarian cancer
Genetic Counselors:
- Under 18
- Not qualified
- Not approved by the PI
Data sourced from ClinicalTrials.gov (NCT04476654). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.