Phase 4
Completed N=44
An Analysis of the Efficacy of a Pre-Emptive Multimodal Pain Regimen in Reducing Acute Post-Operative Pain and Narcotic Pain Medication Requirements in Spine Surgery
Pain, Postoperative · Spine Injuries and Disorders · Narcotic Use
Source: ClinicalTrials.gov NCT04522206 ↗
Enrolled (actual)
44
Serious AEs
0.0%
Results posted
Jul 2022
Primary outcomePrimary: Visual Analogue Scale (VAS) for Pain — 4.8 score on a scale
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
The aim of this study is to investigate the hypothesis that multimodal pain regimen (consisting of acetaminophen, celecoxib, gabapentin, and oxycodone) administered pre-operatively before elective spine surgery significantly decreases acute pain post-operatively as well as decreasing requirements of post-op opioids for pain control in PACU as compared to patients undergoing elective spine surgery without a pre-operative pain regimen.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Visual Analogue Scale (VAS) for Pain |
4.8 | — |
| PRIMARY Opioid Sparing and Rescue Time |
1.5 | — |
| SECONDARY Length of Stay in Hospital |
139 | — |
Eligibility Criteria
Inclusion Criteria
- Undergoing elective spine surgery at NYU Winthrop
- Age over 18 years
Exclusion Criteria
- History of neuromuscular disorders
- History of inflammatory arthropathies
- History of spine metastases or active cancer in spine
- Medical History including any of the following: renal dysfunction, gastric ulcers, hepatic dysfunction, coagulopathic/bleeding disorders, prior adverse or allergic reactions to any of the medications in the study
- Age less than 18 years
Data sourced from ClinicalTrials.gov (NCT04522206). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.