N/A
Completed N=5,176
Framing Clinical Trial Enrollment for Patients With Peripheral Artery Disease
Source: ClinicalTrials.gov NCT04536038 ↗Enrolled (actual)
5,176
Serious AEs
0.1%
Results posted
Dec 2025
Primary outcomePrimary: Enrollment in GAMEPAD Intervention Study — 39; 45 Participants
Summary
It is uncertain whether opt-out framing will increase participation in a clinical trial intended to promote physical activity in patients with peripheral artery disease (PAD). This study will test whether opt-in or opt-out framing of study participation upon initial contact affects the proportion of patients who ultimately enroll in the study and the demographic characteristics of enrolled patients.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Enrollment in GAMEPAD Intervention Study |
39; 45 | — |
Eligibility Criteria
Inclusion Criteria
- At least 18 years of age
- Have been seen in the University of Pennsylvania Health System
- Have an ICD-10 code consistent with peripheral artery disease (I70.2x, I70.3x-I70.7x, I73.9) or peripheral artery disease on their problem list
- Have an email address on file with the University of Pennsylvania Health System
Exclusion Criteria
- Previously indicated unwillingness to be contacted by email for participation in research studies
Data sourced from ClinicalTrials.gov (NCT04536038). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.