N/A Completed N=20 Randomized Treatment

Immunological Response After Shrimp Oral Immunotherapy Treatment

Allergy to Shrimp · Immunotherapy

Source: ClinicalTrials.gov NCT04552522 ↗

Enrolled (actual)

Serious AEs

25.0%

Results posted

Apr 2026

Primary outcomePrimary: Change in Eliciting Dose of Shrimp During Oral Food Challenge — 3233; 25 mg

Summary

Oral immunotherapy is effective in desensitized food allergy. Shrimp allergy is increasing in Thailand. So the purpose of our study is to determine level of specific immunoglobulin E antibodies to shrimp, Immunoglobulin G4 and immunoblot analysis in shrimp allergy patients after shrimp oral immunotherapy.

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Eliciting Dose of Shrimp During Oral Food Challenge	3233; 25	—
SECONDARY Adverse Event From Shrimp Oral Immunotherapy	—	—

Eligibility Criteria

Inclusion Criteria

Age 12 - 40 years old
History of Immunoglobulin E-mediated shrimp allergy > 3 episode/year or disturb quality of life
Positive oral food challenge test for shrimp

Exclusion Criteria

History of shrimp anaphylaxis (include cardiovascular or neurological symptoms)
Shellfish dependent exercise induced anaphylaxis
History of cardiovascular disease, uncontrolled asthma, severe atopic dermatitis
History of Beta-blocker, Angiotensin-converting enzyme inhibitor, Angiotensin receptor blocker, Calcium channel blocker

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04552522). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.