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N/A N=7,103 Randomized Supportive Care

Non-pharmacological Pain Management After Surgery

Surgical Procedure, Unspecified

Enrolled (actual)
7,103
Serious AEs
0.2%
Results posted
Nov 2025
Primary outcome: Primary: PROMIS-CAT Pain — 59.32; 59.96; 56.94; 56.06 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Conversation Guide + Clinical Support (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Mayo Clinic
Primary completion
May 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
PROMIS-CAT Pain
59.32; 59.96; 56.94; 56.06; 53.08; 53.29
PRIMARY
PROMIS-CAT Physical Function
40.50; 39.50; 38.44; 39.68; 42.44; 40.79
PRIMARY
PROMIS-CAT Anxiety
50.72; 51.85; 51.93; 51.63; 51.21; 51.75
PRIMARY
Use of Non-Pharmacological Pain Control Modalities
23; 752; 58; 2549; 721; 16058
PRIMARY
Opioid Use
16158; 26035; 19082; 30414; 22299; 37639

Summary

The purpose of this study is to test the impact of a bundled NOHARM Conversation Guide with clinical decision support intervention embedded within an Electronic Health Record (EHR) on pain and function 3 months following surgery.

Eligibility Criteria

Inclusion Criteria

  • All patients 18 years of age and older.
  • Must be undergoing qualifying surgeries at participating sites.
  • Patients under 18 years of age.

Exclusion Criteria

  • Patients under 18 years of age.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04570371). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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