N/A
Completed N=13
Cognitive-based Prosthetics to Improve Grasp and Reaching After SCI
Spinal Cord Injuries · Hand Weakness
Source: ClinicalTrials.gov NCT04577573 ↗
Enrolled (actual)
13
Serious AEs
0.0%
Results posted
Apr 2025
Primary outcomePrimary: Percent Change in Time to Achieve Secure Grasp (Cognition Glove Only) — 39.9; -14.6; 10.1 % change in time to secure grasp
Summary
Rehabilitation of functional movements after spinal cord injury (SCI) requires commitment and engagement to the processes of physical therapy. Outcomes may be improved by techniques that strengthen cognitive connections between users and physical therapy exercises.
The investigators will investigate combinations of virtual reality and innovative wearable technology to accelerate rehabilitation of hand grasp and reach. These devices use multi-sensory feedback to enhance the sense of agency, or feelings of control, and better train movements during physical rehabilitation exercises. The investigators will measure the effect of these devices on improving the speed, efficiency, and accuracy of performed movements in Veterans with SCI.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percent Change in Time to Achieve Secure Grasp (Cognition Glove Only) |
39.9; -14.6; 10.1 | — |
| PRIMARY Percent Change in Time to Complete Pick-up and Placement of Object-Cognition Glove |
20.2; 7.9; -24.4 | — |
| PRIMARY Percent Change in Time to Complete Trial-Sensory Brace |
18.6; 3.3 | — |
| SECONDARY Percent Change in Motion Pathlength in Moving Object-Cognition Glove |
39.1; 21.9; -12.4 | — |
| SECONDARY Percent Change in Motion Pathlength Toward Virtual Targets-Sensory Brace |
17.7; 1.4 | — |
| SECONDARY Error in Placing Object Onto Target (Cognition Glove Only) |
0; 0; 0 | — |
Eligibility Criteria
Inclusion Criteria
- SCI occurred greater than 12 months ago
- SCI occurred between levels C1-T1
- Hand weakness: score of 2, 3, or 4 out of 5 on manual muscle testing of finger extension, finger flexion, or finger abduction in either hand
Exclusion Criteria
- History of other serious brain or spinal cord injuries
- History of seizures
- Ventilator dependence; open tracheostomy
- Use of medications that significantly lower seizure threshold
- History of significant cognitive deficits
- Open skin lesions over the face, neck, shoulders, arms, or hands
- Pregnancy
Data sourced from ClinicalTrials.gov (NCT04577573). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.